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Page 1
Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.
Cadby G, Giles C, Melton PE, Huynh K, Mellett NA, Duong T, Nguyen A, Cinel M, Smith A, Olshansky G, Wang T, Brozynska M, Inouye M, McCarthy NS, Ariff A, Hung J, Hui J, Beilby J, Dubé MP, Watts GF, Shah S, Wray NR, Lim WLF, Chatterjee P, Martins I, Laws SM, Porter T, Vacher M, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Taddei K, Arnold M, Kastenmüller G, Nho K, Saykin AJ, Han X, Kaddurah-Daouk R, Martins RN, Blangero J, Meikle PJ, Moses EK. Cadby G, et al. Nat Commun. 2022 Jun 6;13(1):3124. doi: 10.1038/s41467-022-30875-7. Nat Commun. 2022. PMID: 35668104 Free PMC article.
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease.
Huynh K, Lim WLF, Giles C, Jayawardana KS, Salim A, Mellett NA, Smith AAT, Olshansky G, Drew BG, Chatterjee P, Martins I, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Arnold M, Nho K, Saykin AJ, Baillie R, Han X, Kaddurah-Daouk R, Martins RN, Meikle PJ. Huynh K, et al. Nat Commun. 2020 Nov 10;11(1):5698. doi: 10.1038/s41467-020-19473-7. Nat Commun. 2020. PMID: 33173055 Free PMC article.
Sex and APOE ε4 genotype modify the Alzheimer's disease serum metabolome.
Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, MahmoudianDehkordi S, Louie G, Moseley MA, Thompson JW, John-Williams LS, Tenenbaum JD, Blach C, Chang R, Brinton RD, Baillie R, Han X, Trojanowski JQ, Shaw LM, Martins R, Weiner MW, Trushina E, Toledo JB, Meikle PJ, Bennett DA, Krumsiek J, Doraiswamy PM, Saykin AJ, Kaddurah-Daouk R, Kastenmüller G. Arnold M, et al. Nat Commun. 2020 Mar 2;11(1):1148. doi: 10.1038/s41467-020-14959-w. Nat Commun. 2020. PMID: 32123170 Free PMC article.
Multi-Omic analyses characterize the ceramide/sphingomyelin pathway as a therapeutic target in Alzheimer's disease.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, Brauner B, Louie G, Kueider-Paisley A, Suhre K, Saykin AJ, Ekroos K, Meikle PJ, Hood L, Price ND; Alzheimer’s Disease Metabolomics Consortium; Doraiswamy PM, Funk CC, Hernández AI, Kastenmüller G, Baillie R, Han X, Kaddurah-Daouk R. Baloni P, et al. Commun Biol. 2022 Oct 8;5(1):1074. doi: 10.1038/s42003-022-04011-6. Commun Biol. 2022. PMID: 36209301 Free PMC article.
APOE ε2 resilience for Alzheimer's disease is mediated by plasma lipid species: Analysis of three independent cohort studies.
Wang T, Huynh K, Giles C, Mellett NA, Duong T, Nguyen A, Lim WLF, Smith AA, Olshansky G, Cadby G, Hung J, Hui J, Beilby J, Watts GF, Chatterjee P, Martins I, Laws SM, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Taddei K, Doré V, Fripp J, Arnold M, Kastenmüller G, Nho K, Saykin AJ, Baillie R, Han X, Martins RN, Moses EK, Kaddurah-Daouk R, Meikle PJ. Wang T, et al. Alzheimers Dement. 2022 Nov;18(11):2151-2166. doi: 10.1002/alz.12538. Epub 2022 Jan 25. Alzheimers Dement. 2022. PMID: 35077012 Free PMC article.
Serum metabolites associated with brain amyloid beta deposition, cognition and dementia progression.
Nho K, Kueider-Paisley A, Arnold M, MahmoudianDehkordi S, Risacher SL, Louie G, Blach C, Baillie R, Han X, Kastenmüller G, Doraiswamy PM, Kaddurah-Daouk R, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative and on behalf of the Alzheimer Disease Metabolomics Consortium. Nho K, et al. Brain Commun. 2021 Jul 2;3(3):fcab139. doi: 10.1093/braincomms/fcab139. eCollection 2021. Brain Commun. 2021. PMID: 34396103 Free PMC article.
Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology.
Barupal DK, Baillie R, Fan S, Saykin AJ, Meikle PJ, Arnold M, Nho K, Fiehn O, Kaddurah-Daouk R; Alzheimer Disease Metabolomics Consortium. Barupal DK, et al. Alzheimers Dement (Amst). 2019 Sep 5;11:619-627. doi: 10.1016/j.dadm.2019.07.002. eCollection 2019 Dec. Alzheimers Dement (Amst). 2019. PMID: 31517024 Free PMC article.
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[No authors listed] [No authors listed] PMID: 35109151
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[No authors listed] [No authors listed] PMID: 35109201
185 results