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Inhibition of type 1 immunity with tofacitinib is associated with marked improvement in longstanding sarcoidosis.
Damsky W, Wang A, Kim DJ, Young BD, Singh K, Murphy MJ, Daccache J, Clark A, Ayasun R, Ryu C, McGeary MK, Odell ID, Fazzone-Chettiar R, Pucar D, Homer R, Gulati M, Miller EJ, Bosenberg M, Flavell RA, King B. Damsky W, et al. Among authors: gulati m. Nat Commun. 2022 Jun 6;13(1):3140. doi: 10.1038/s41467-022-30615-x. Nat Commun. 2022. PMID: 35668129 Free PMC article. Clinical Trial.
Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.
Reilkoff RA, Peng H, Murray LA, Peng X, Russell T, Montgomery R, Feghali-Bostwick C, Shaw A, Homer RJ, Gulati M, Mathur A, Elias JA, Herzog EL. Reilkoff RA, et al. Among authors: gulati m. Am J Respir Crit Care Med. 2013 Jan 15;187(2):180-8. doi: 10.1164/rccm.201206-1109OC. Epub 2012 Dec 6. Am J Respir Crit Care Med. 2013. PMID: 23220917 Free PMC article.
Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.
Peng X, Moore M, Mathur A, Zhou Y, Sun H, Gan Y, Herazo-Maya JD, Kaminski N, Hu X, Pan H, Ryu C, Osafo-Addo A, Homer RJ, Feghali-Bostwick C, Fares WH, Gulati M, Hu B, Lee CG, Elias JA, Herzog EL. Peng X, et al. Among authors: gulati m. FASEB J. 2016 Dec;30(12):4056-4070. doi: 10.1096/fj.201600373R. Epub 2016 Sep 8. FASEB J. 2016. PMID: 27609773 Free PMC article.
These data demonstrate the previously unrecognized observation that PLXNC1 deficiency permits Syt7-mediated macrophage migration and enhances mammalian lung fibrosis.-Peng, X., Moore, M., Mathur, A., Zhou, Y., Sun, H., Gan, Y., Herazo-Maya, J. D., Kaminski, N., Hu, X., Pan …
These data demonstrate the previously unrecognized observation that PLXNC1 deficiency permits Syt7-mediated macrophage migration and enhance …
Validation of the prognostic value of MMP-7 in idiopathic pulmonary fibrosis.
Tzouvelekis A, Herazo-Maya JD, Slade M, Chu JH, Deiuliis G, Ryu C, Li Q, Sakamoto K, Ibarra G, Pan H, Gulati M, Antin-Ozerkis D, Herzog EL, Kaminski N. Tzouvelekis A, et al. Among authors: gulati m. Respirology. 2017 Apr;22(3):486-493. doi: 10.1111/resp.12920. Epub 2016 Oct 19. Respirology. 2017. PMID: 27761978 Free PMC article.
Plasma mitochondrial DNA is associated with extrapulmonary sarcoidosis.
Ryu C, Brandsdorfer C, Adams T, Hu B, Kelleher DW, Yaggi M, Manning EP, Walia A, Reeves B, Pan H, Winkler J, Minasyan M, Dela Cruz CS, Kaminski N, Gulati M, Herzog EL. Ryu C, et al. Among authors: gulati m. Eur Respir J. 2019 Aug 29;54(2):1801762. doi: 10.1183/13993003.01762-2018. Print 2019 Aug. Eur Respir J. 2019. PMID: 31273041 Free PMC article.
Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis.
Gao R, Peng X, Perry C, Sun H, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL. Gao R, et al. Among authors: gulati m. J Clin Invest. 2021 Jan 4;131(1):e136542. doi: 10.1172/JCI136542. J Clin Invest. 2021. PMID: 33393489 Free PMC article.
Elevated IL-15 concentrations in the sarcoidosis lung are independent of granuloma burden and disease phenotypes.
Minasyan M, Sharma L, Pivarnik T, Liu W, Adams T, Bermejo S, Peng X, Liu A, Ishikawa G, Perry C, Kaminski N, Gulati M, Herzog EL, Dela Cruz CS, Ryu C. Minasyan M, et al. Among authors: gulati m. Am J Physiol Lung Cell Mol Physiol. 2021 Jun 1;320(6):L1137-L1146. doi: 10.1152/ajplung.00575.2020. Epub 2021 Apr 14. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33851886 Free PMC article.
Non-steroidal treatment of cardiac sarcoidosis: A systematic review.
Gallegos C, Oikonomou EK, Grimshaw A, Gulati M, Young BD, Miller EJ. Gallegos C, et al. Among authors: gulati m. Int J Cardiol Heart Vasc. 2021 Apr 29;34:100782. doi: 10.1016/j.ijcha.2021.100782. eCollection 2021 Jun. Int J Cardiol Heart Vasc. 2021. PMID: 33997256 Free PMC article.
760 results