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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer's-like pathology in mouse and fly APP overexpression models.
Chocron ES, Munkácsy E, Kim HS, Karpowicz P, Jiang N, Van Skike CE, DeRosa N, Banh AQ, Palavicini JP, Wityk P, Kalinowski L, Galvan V, Osmulski PA, Jankowska E, Gaczynska M, Pickering AM. Chocron ES, et al. Among authors: palavicini jp. Sci Adv. 2022 Jun 10;8(23):eabk2252. doi: 10.1126/sciadv.abk2252. Epub 2022 Jun 8. Sci Adv. 2022. PMID: 35675410 Free PMC article.
Multi-omics analyses reveal novel effects of PLCγ2 deficiency in the mouse brain.
Hopp SC, Rogers JG, Smith S, Campos G, Miller H, Barannikov S, Kuri EG, Wang H, Han X, Bieniek KF, Weintraub ST, Palavicini JP. Hopp SC, et al. Among authors: palavicini jp. bioRxiv [Preprint]. 2023 Dec 8:2023.12.06.570499. doi: 10.1101/2023.12.06.570499. bioRxiv. 2023. PMID: 38106102 Free PMC article. Preprint.
Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered metabolism, cell senescence, and nonalcoholic fatty liver disease.
Xu G, Quan S, Schell J, Gao Y, Varmazyad M, Sreenivas P, Cruz D, Jiang H, Pan M, Han X, Palavicini JP, Zhao P, Sun X, Marchant ED, Rasmussen BB, Li G, Katsumura S, Morita M, Munkácsy E, Horikoshi N, Chocron ES, Gius D. Xu G, et al. Among authors: palavicini jp. Sci Adv. 2024 May 17;10(20):eadj5942. doi: 10.1126/sciadv.adj5942. Epub 2024 May 17. Sci Adv. 2024. PMID: 38758779 Free PMC article.
34 results