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The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer.
Patel SA, Hirosue S, Rodrigues P, Vojtasova E, Richardson EK, Ge J, Syafruddin SE, Speed A, Papachristou EK, Baker D, Clarke D, Purvis S, Wesolowski L, Dyas A, Castillon L, Caraffini V, Bihary D, Yong C, Harrison DJ, Stewart GD, Machiela MJ, Purdue MP, Chanock SJ, Warren AY, Samarajiwa SA, Carroll JS, Vanharanta S. Patel SA, et al. Among authors: baker d. Nature. 2022 Jun;606(7916):999-1006. doi: 10.1038/s41586-022-04809-8. Epub 2022 Jun 8. Nature. 2022. PMID: 35676472 Free PMC article.
Rare variant associations with plasma protein levels in the UK Biobank.
Dhindsa RS, Burren OS, Sun BB, Prins BP, Matelska D, Wheeler E, Mitchell J, Oerton E, Hristova VA, Smith KR, Carss K, Wasilewski S, Harper AR, Paul DS, Fabre MA, Runz H, Viollet C, Challis B, Platt A; AstraZeneca Genomics Initiative; Vitsios D, Ashley EA, Whelan CD, Pangalos MN, Wang Q, Petrovski S. Dhindsa RS, et al. Nature. 2023 Oct;622(7982):339-347. doi: 10.1038/s41586-023-06547-x. Epub 2023 Oct 4. Nature. 2023. PMID: 37794183 Free PMC article.
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amossé Q, Ceyzériat K, Badina AM, Kövari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM, Smith AM, Barnes SJ, Hampton DW, van der Valk P, Jacobson S, Howell OW, Baker D, Kipp M, Kaddatz H, Tournier BB, Millet P, Matthews PM, Moore CS, Amor S, Owen DR. Nutma E, et al. Among authors: baker d. Nat Commun. 2023 Aug 28;14(1):5247. doi: 10.1038/s41467-023-40937-z. Nat Commun. 2023. PMID: 37640701 Free PMC article.
Endowments are necessary for museums to thrive.
Baker DJ, Sabloff JA, Raven PA. Baker DJ, et al. Nature. 2007 May 24;447(7143):376. doi: 10.1038/447376b. Nature. 2007. PMID: 17522653 No abstract available.
Straight talk with...David Baker.
Baker D, Khamsi R. Baker D, et al. Nat Med. 2012 Nov;18(11):1599. doi: 10.1038/nm1112-1599. Nat Med. 2012. PMID: 23135501
De novo design of buttressed loops for sculpting protein functions.
Jiang H, Jude KM, Wu K, Fallas J, Ueda G, Brunette TJ, Hicks DR, Pyles H, Yang A, Carter L, Lamb M, Li X, Levine PM, Stewart L, Garcia KC, Baker D. Jiang H, et al. Among authors: baker d. Nat Chem Biol. 2024 May 30. doi: 10.1038/s41589-024-01632-2. Online ahead of print. Nat Chem Biol. 2024. PMID: 38816644
De novo designed proteins neutralize lethal snake venom toxins.
Baker D, Torres SV, Valle MB, Mackessy S, Menzies S, Casewell N, Ahmadi S, Burlet N, Muratspahić E, Sappington I, Overath M, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera A, Kang A, Brackenbrough E, Cardoso I, Crittenden E, Edge R, Decarreau J, Ragotte R, Pillai A, Abedi M, Han H, Gerben S, Murray A, Skotheim R, Stuart L, Stewart L, Fryer T, Jenkins T. Baker D, et al. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. PMID: 38798548 Free PMC article. Preprint.
Senescent Macrophages Release Inflammatory Cytokines and RNA-Loaded Extracellular Vesicles to Circumvent Fibroblast Senescence.
Laliberté C, Bossé B, Bourdeau V, Prieto LI, Perron-Deshaies G, Vuong-Robillard N, Igelmann S, Aguilar LC, Oeffinger M, Baker DJ, DesGroseillers L, Ferbeyre G. Laliberté C, et al. Among authors: baker dj. Biomedicines. 2024 May 14;12(5):1089. doi: 10.3390/biomedicines12051089. Biomedicines. 2024. PMID: 38791051 Free PMC article.
5,660 results