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The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability.
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR, Carr SA, Lindquist S, De Jager PL, Bartel DP, Myers CL, Greenamyre JT, Feany MB, Sunyaev SR, Chung CY, Khurana V. Hallacli E, et al. Among authors: jiang x. Cell. 2022 Jun 9;185(12):2035-2056.e33. doi: 10.1016/j.cell.2022.05.008. Cell. 2022. PMID: 35688132 Free PMC article.
A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Nuber S, Chung CY, Tardiff DF, Bechade PA, McCaffery TD, Shimanaka K, Choi J, Chang B, Raja W, Neves E, Burke C, Jiang X, Xu P, Khurana V, Dettmer U, Fanning S, Rhodes KJ, Selkoe DJ, Scannevin RH. Nuber S, et al. Among authors: jiang x. Neurotherapeutics. 2022 Apr;19(3):1018-1036. doi: 10.1007/s13311-022-01199-7. Epub 2022 Apr 20. Neurotherapeutics. 2022. PMID: 35445353 Free PMC article.
Correction to: A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Nuber S, Chung CY, Tardiff DF, Bechade PA, McCaffery TD, Shimanaka K, Choi J, Chang B, Raja W, Neves E, Burke C, Jiang X, Xu P, Khurana V, Dettmer U, Fanning S, Rhodes KJ, Selkoe DJ, Scannevin RH. Nuber S, et al. Among authors: jiang x. Neurotherapeutics. 2022 Jul;19(4):1434. doi: 10.1007/s13311-022-01268-x. Neurotherapeutics. 2022. PMID: 35792968 Free PMC article. No abstract available.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Jambeau M, Meyer KD, Hruska-Plochan M, Tabet R, Lee CZ, Ray-Soni A, Aguilar C, Savage K, Mishra N, Cavegn N, Borter P, Lin CC, Jansen-West KR, Jiang J, Freyermuth F, Li N, De Rossi P, Pérez-Berlanga M, Jiang X, Daughrity LM, Pereira J, Narayanan S, Gu Y, Dhokai S, Dalkilic-Liddle I, Maniecka Z, Weber J, Workman M, McAlonis-Downes M, Berezovski E, Zhang YJ, Berry J, Wainger BJ, Kankel MW, Rushe M, Hock C, Nitsch RM, Cleveland DW, Petrucelli L, Gendron TF, Montrasio F, Grimm J, Polymenidou M, Lagier-Tourenne C. Jambeau M, et al. Among authors: jiang x, jiang j. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2123487119. doi: 10.1073/pnas.2123487119. Epub 2022 Dec 1. Proc Natl Acad Sci U S A. 2022. PMID: 36454749 Free PMC article.
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