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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9.
Cell. 2022.
PMID: 35688146
Free PMC article.
Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination.
Huang KL, Jee D, Stein CB, Elrod ND, Henriques T, Mascibroda LG, Baillat D, Russell WK, Adelman K, Wagner EJ.
Huang KL, et al. Among authors: mascibroda lg.
Mol Cell. 2020 Oct 15;80(2):345-358.e9. doi: 10.1016/j.molcel.2020.08.016. Epub 2020 Sep 22.
Mol Cell. 2020.
PMID: 32966759
Free PMC article.
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Integrator subunit 4 is a 'Symplekin-like' scaffold that associates with INTS9/11 to form the Integrator cleavage module.
Albrecht TR, Shevtsov SP, Wu Y, Mascibroda LG, Peart NJ, Huang KL, Sawyer IA, Tong L, Dundr M, Wagner EJ.
Albrecht TR, et al. Among authors: mascibroda lg.
Nucleic Acids Res. 2018 May 4;46(8):4241-4255. doi: 10.1093/nar/gky100.
Nucleic Acids Res. 2018.
PMID: 29471365
Free PMC article.
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INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ.
Mascibroda LG, et al.
Nat Commun. 2022 Oct 13;13(1):6054. doi: 10.1038/s41467-022-33547-8.
Nat Commun. 2022.
PMID: 36229431
Free PMC article.
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Explorative Study on Isolation and Characterization of a Microviridae G4 Bacteriophage, EMCL318, against Multi-Drug-resistant Escherichia coli 15-318.
Ghosh S, Persad E, Shiue TY, Lam C, Islam A, Mascibroda LG, Sherman MB, Smith T, Cheeptham N.
Ghosh S, et al. Among authors: mascibroda lg.
Antibiotics (Basel). 2018 Oct 26;7(4):92. doi: 10.3390/antibiotics7040092.
Antibiotics (Basel). 2018.
PMID: 30373114
Free PMC article.
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Selective CK1α degraders exert antiproliferative activity against a broad range of human cancer cell lines.
Nishiguchi G, Mascibroda LG, Young SM, Caine EA, Abdelhamed S, Kooijman JJ, Miller DJ, Das S, McGowan K, Mayasundari A, Shi Z, Barajas JM, Hiltenbrand R, Aggarwal A, Chang Y, Mishra V, Narina S, Thomas M, Loughran AJ, Kalathur R, Yu K, Zhou S, Wang X, High AA, Peng J, Pruett-Miller SM, Daniels DL, Urh M, Shelat AA, Mullighan CG, Riching KM, Zaman GJR, Fischer M, Klco JM, Rankovic Z.
Nishiguchi G, et al. Among authors: mascibroda lg.
Nat Commun. 2024 Jan 16;15(1):482. doi: 10.1038/s41467-024-44698-1.
Nat Commun. 2024.
PMID: 38228616
Free PMC article.
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