Ottenhoff TH - Search Results

1

Host Transcriptional Signatures Predict Etiology in Community-Acquired Pneumonia: Potential Antibiotic Stewardship Tools.

Siljan WW, Sivakumaran D, Ritz C, Jenum S, Ottenhoff TH, Ulvestad E, Holter JC, Heggelund L, Grewal HM. Siljan WW, et al. Among authors: ottenhoff th. Biomark Insights. 2022 Jun 6;17:11772719221099130. doi: 10.1177/11772719221099130. eCollection 2022. Biomark Insights. 2022. PMID: 35693251 Free PMC article.

2

Approaching a diagnostic point-of-care test for pediatric tuberculosis through evaluation of immune biomarkers across the clinical disease spectrum.

Jenum S, Dhanasekaran S, Lodha R, Mukherjee A, Kumar Saini D, Singh S, Singh V, Medigeshi G, Haks MC, Ottenhoff TH, Doherty TM, Kabra SK, Ritz C, Grewal HM. Jenum S, et al. Among authors: ottenhoff th. Sci Rep. 2016 Jan 4;6:18520. doi: 10.1038/srep18520. Sci Rep. 2016. PMID: 26725873 Free PMC article.

3

BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome.

Jenum S, Bakken R, Dhanasekaran S, Mukherjee A, Lodha R, Singh S, Singh V, Haks MC, Ottenhoff TH, Kabra SK, Doherty TM, Ritz C, Grewal HM. Jenum S, et al. Among authors: ottenhoff th. Sci Rep. 2016 Dec 12;6:38841. doi: 10.1038/srep38841. Sci Rep. 2016. PMID: 27941850 Free PMC article.

4

Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children.

Gjøen JE, Jenum S, Sivakumaran D, Mukherjee A, Macaden R, Kabra SK, Lodha R, Ottenhoff THM, Haks MC, Doherty TM, Ritz C, Grewal HMS. Gjøen JE, et al. Sci Rep. 2017 Jul 19;7(1):5839. doi: 10.1038/s41598-017-05057-x. Sci Rep. 2017. PMID: 28724962 Free PMC article. Clinical Trial.

5

Combining host-derived biomarkers with patient characteristics improves signature performance in predicting tuberculosis treatment outcomes.

Sivakumaran D, Jenum S, Vaz M, Selvam S, Ottenhoff THM, Haks MC, Malherbe ST, Doherty TM, Ritz C, Grewal HMS. Sivakumaran D, et al. Commun Biol. 2020 Jul 9;3(1):359. doi: 10.1038/s42003-020-1087-x. Commun Biol. 2020. PMID: 32647325 Free PMC article.

6

Host Blood RNA Transcript and Protein Signatures for Sputum-Independent Diagnostics of Tuberculosis in Adults.

Sivakumaran D, Ritz C, Gjøen JE, Vaz M, Selvam S, Ottenhoff THM, Doherty TM, Jenum S, Grewal HMS. Sivakumaran D, et al. Front Immunol. 2021 Feb 4;11:626049. doi: 10.3389/fimmu.2020.626049. eCollection 2020. Front Immunol. 2021. PMID: 33613569 Free PMC article.

7

Identification of biomarkers for tuberculosis disease using a novel dual-color RT-MLPA assay.

Joosten SA, Goeman JJ, Sutherland JS, Opmeer L, de Boer KG, Jacobsen M, Kaufmann SH, Finos L, Magis-Escurra C, Ota MO, Ottenhoff TH, Haks MC. Joosten SA, et al. Among authors: ottenhoff th. Genes Immun. 2012 Jan;13(1):71-82. doi: 10.1038/gene.2011.64. Epub 2011 Sep 29. Genes Immun. 2012. PMID: 21956656

8

Repurposing Tamoxifen as Potential Host-Directed Therapeutic for Tuberculosis.

Boland R, Heemskerk MT, Forn-Cuní G, Korbee CJ, Walburg KV, Esselink JJ, Carvalho Dos Santos C, de Waal AM, van der Hoeven DCM, van der Sar E, de Ries AS, Xie J, Spaink HP, van der Vaart M, Haks MC, Meijer AH, Ottenhoff THM. Boland R, et al. mBio. 2023 Feb 28;14(1):e0302422. doi: 10.1128/mbio.03024-22. Epub 2022 Dec 7. mBio. 2023. PMID: 36475748 Free PMC article.

9

Host-directed therapy to combat mycobacterial infections.

Kilinç G, Saris A, Ottenhoff THM, Haks MC. Kilinç G, et al. Immunol Rev. 2021 May;301(1):62-83. doi: 10.1111/imr.12951. Epub 2021 Feb 9. Immunol Rev. 2021. PMID: 33565103 Free PMC article. Review.

10

Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification.

Gliddon HD, Kaforou M, Alikian M, Habgood-Coote D, Zhou C, Oni T, Anderson ST, Brent AJ, Crampin AC, Eley B, Heyderman R, Kern F, Langford PR, Ottenhoff THM, Hibberd ML, French N, Wright VJ, Dockrell HM, Coin LJ, Wilkinson RJ, Levin M. Gliddon HD, et al. Front Immunol. 2021 Mar 2;12:637164. doi: 10.3389/fimmu.2021.637164. eCollection 2021. Front Immunol. 2021. PMID: 33763081 Free PMC article.

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