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Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function.
Cerniauskas E, Kurzawa-Akanbi M, Xie L, Hallam D, Moya-Molina M, White K, Steel D, Doherty M, Whitfield P, Al-Aama J, Armstrong L, Kavanagh D, Lambris JD, Korolchuk VI, Harris C, Lako M. Cerniauskas E, et al. Among authors: harris c. Stem Cells Transl Med. 2020 Dec;9(12):1585-1603. doi: 10.1002/sctm.20-0211. Epub 2020 Aug 20. Stem Cells Transl Med. 2020. PMID: 32815311 Free PMC article.
An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access.
Jones AV, Curtiss D, Harris C, Southerington T, Hautalahti M, Wihuri P, Mäkelä J, Kallionpää RE, Makkonen E, Knopp T, Mannermaa A, Mäkinen E, Moilanen AM, Tezel TH; SCOPE Study group; Waheed NK. Jones AV, et al. Among authors: harris c. PLoS One. 2022 Sep 6;17(9):e0272260. doi: 10.1371/journal.pone.0272260. eCollection 2022. PLoS One. 2022. PMID: 36067162 Free PMC article.
4,577 results