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Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Büttner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP. Thomalla D, et al. Among authors: frenzel lp. Blood. 2022 Nov 17;140(20):2113-2126. doi: 10.1182/blood.2021014304. Blood. 2022. PMID: 35704690 Free PMC article.
miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia.
Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM. Pallasch CP, et al. Among authors: frenzel lp. Blood. 2009 Oct 8;114(15):3255-64. doi: 10.1182/blood-2009-06-229898. Epub 2009 Aug 19. Blood. 2009. PMID: 19692702 Free PMC article.
Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies.
Leskov I, Pallasch CP, Drake A, Iliopoulou BP, Souza A, Shen CH, Schweighofer CD, Abruzzo L, Frenzel LP, Wendtner CM, Hemann MT, Chen J. Leskov I, et al. Among authors: frenzel lp. Oncogene. 2013 Feb 21;32(8):1066-1072. doi: 10.1038/onc.2012.117. Epub 2012 Apr 9. Oncogene. 2013. PMID: 22484426 Free PMC article.
43 results