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MERTK activation drives osimertinib resistance in EGFR-mutant non-small cell lung cancer.
J Clin Invest. 2022 Aug 1;132(15):e150517. doi: 10.1172/JCI150517.
J Clin Invest. 2022.
PMID: 35708914
Free PMC article.
Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology.
Da C, Zhang D, Stashko M, Vasileiadi E, Parker RE, Minson KA, Huey MG, Huelse JM, Hunter D, Gilbert TSK, Norris-Drouin J, Miley M, Herring LE, Graves LM, DeRyckere D, Earp HS, Graham DK, Frye SV, Wang X, Kireev D.
Da C, et al. Among authors: huelse jm.
J Am Chem Soc. 2019 Oct 2;141(39):15700-15709. doi: 10.1021/jacs.9b08660. Epub 2019 Sep 20.
J Am Chem Soc. 2019.
PMID: 31497954
Free PMC article.
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MERTK in cancer therapy: Targeting the receptor tyrosine kinase in tumor cells and the immune system.
Huelse JM, Fridlyand DM, Earp S, DeRyckere D, Graham DK.
Huelse JM, et al.
Pharmacol Ther. 2020 Sep;213:107577. doi: 10.1016/j.pharmthera.2020.107577. Epub 2020 May 14.
Pharmacol Ther. 2020.
PMID: 32417270
Free PMC article.
Review.
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Corrigendum to "MERTK in cancer therapy: Targeting the receptor tyrosine kinase in tumor cells and the immune system" [Pharmacology & Therapeutics 213 (2020) 107577].
Huelse JM, Fridlyand DM, Earp S, DeRyckere D, Graham DK.
Huelse JM, et al.
Pharmacol Ther. 2021 Sep;225:107822. doi: 10.1016/j.pharmthera.2021.107822. Epub 2021 Mar 10.
Pharmacol Ther. 2021.
PMID: 33714535
No abstract available.
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TAM family kinases as therapeutic targets at the interface of cancer and immunity.
DeRyckere D, Huelse JM, Earp HS, Graham DK.
DeRyckere D, et al. Among authors: huelse jm.
Nat Rev Clin Oncol. 2023 Nov;20(11):755-779. doi: 10.1038/s41571-023-00813-7. Epub 2023 Sep 4.
Nat Rev Clin Oncol. 2023.
PMID: 37667010
Review.
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