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Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques.
Walker-Sperling VEK, Mercado NB, Chandrashekar A, Borducchi EN, Liu J, Nkolola JP, Lewis M, Murry JP, Yang Y, Geleziunas R, Robb ML, Michael NL, Pau MG, Wegmann F, Schuitemaker H, Fray EJ, Kumar MR, Siliciano JD, Siliciano RF, Barouch DH. Walker-Sperling VEK, et al. Among authors: geleziunas r. Nat Commun. 2022 Jun 16;13(1):3463. doi: 10.1038/s41467-022-31196-5. Nat Commun. 2022. PMID: 35710819 Free PMC article.
Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.
Whitney JB, Hill AL, Sanisetty S, Penaloza-MacMaster P, Liu J, Shetty M, Parenteau L, Cabral C, Shields J, Blackmore S, Smith JY, Brinkman AL, Peter LE, Mathew SI, Smith KM, Borducchi EN, Rosenbloom DI, Lewis MG, Hattersley J, Li B, Hesselgesser J, Geleziunas R, Robb ML, Kim JH, Michael NL, Barouch DH. Whitney JB, et al. Among authors: geleziunas r. Nature. 2014 Aug 7;512(7512):74-7. doi: 10.1038/nature13594. Epub 2014 Jul 20. Nature. 2014. PMID: 25042999 Free PMC article.
Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys.
Borducchi EN, Cabral C, Stephenson KE, Liu J, Abbink P, Ng'ang'a D, Nkolola JP, Brinkman AL, Peter L, Lee BC, Jimenez J, Jetton D, Mondesir J, Mojta S, Chandrashekar A, Molloy K, Alter G, Gerold JM, Hill AL, Lewis MG, Pau MG, Schuitemaker H, Hesselgesser J, Geleziunas R, Kim JH, Robb ML, Michael NL, Barouch DH. Borducchi EN, et al. Among authors: geleziunas r. Nature. 2016 Dec 8;540(7632):284-287. doi: 10.1038/nature20583. Epub 2016 Nov 9. Nature. 2016. PMID: 27841870 Free PMC article.
Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.
Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, Hesselgesser J, Li W, Lewis MG, Alter G, Geleziunas R, Barouch DH. Borducchi EN, et al. Among authors: geleziunas r. Nature. 2018 Nov;563(7731):360-364. doi: 10.1038/s41586-018-0600-6. Epub 2018 Oct 3. Nature. 2018. PMID: 30283138 Free PMC article.
Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys.
Borducchi EN, Liu J, Nkolola JP, Cadena AM, Yu WH, Fischinger S, Broge T, Abbink P, Mercado NB, Chandrashekar A, Jetton D, Peter L, McMahan K, Moseley ET, Bekerman E, Hesselgesser J, Li W, Lewis MG, Alter G, Geleziunas R, Barouch DH. Borducchi EN, et al. Among authors: geleziunas r. Nature. 2018 Dec;564(7734):E8. doi: 10.1038/s41586-018-0721-y. Nature. 2018. PMID: 30397346
Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques.
Abbink P, Mercado NB, Nkolola JP, Peterson RL, Tuyishime H, McMahan K, Moseley ET, Borducchi EN, Chandrashekar A, Bondzie EA, Agarwal A, Belli AJ, Reimann KA, Keele BF, Geleziunas R, Lewis MG, Barouch DH. Abbink P, et al. Among authors: geleziunas r. Science. 2019 Sep 6;365(6457):1029-1033. doi: 10.1126/science.aaw8562. Epub 2019 Sep 5. Science. 2019. PMID: 31488689 Free PMC article.
Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.
Bricker KM, Obregon-Perko V, Uddin F, Williams B, Uffman EA, Garrido C, Fouda GG, Geleziunas R, Robb M, Michael N, Barouch DH, Chahroudi A. Bricker KM, et al. Among authors: geleziunas r. PLoS Pathog. 2020 Oct 26;16(10):e1008954. doi: 10.1371/journal.ppat.1008954. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33104758 Free PMC article.
TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption.
Hsu DC, Schuetz A, Imerbsin R, Silsorn D, Pegu A, Inthawong D, Sopanaporn J, Visudhiphan P, Chuenarom W, Keawboon B, Shi W, Robb ML, Mascola JR, Geleziunas R, Koup RA, Barouch DH, Michael NL, Vasan S. Hsu DC, et al. Among authors: geleziunas r. PLoS Pathog. 2021 Feb 18;17(2):e1009339. doi: 10.1371/journal.ppat.1009339. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33600506 Free PMC article.
105 results