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eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Lapointe CP, Grosely R, Sokabe M, Alvarado C, Wang J, Montabana E, Villa N, Shin BS, Dever TE, Fraser CS, Fernández IS, Puglisi JD. Lapointe CP, et al. Nature. 2022 Jul;607(7917):185-190. doi: 10.1038/s41586-022-04858-z. Epub 2022 Jun 22. Nature. 2022. PMID: 35732735 Free PMC article.
RACK1 on and off the ribosome.
Johnson AG, Lapointe CP, Wang J, Corsepius NC, Choi J, Fuchs G, Puglisi JD. Johnson AG, et al. Among authors: lapointe cp. RNA. 2019 Jul;25(7):881-895. doi: 10.1261/rna.071217.119. Epub 2019 Apr 25. RNA. 2019. PMID: 31023766 Free PMC article.
eIF5B gates the transition from translation initiation to elongation.
Wang J, Johnson AG, Lapointe CP, Choi J, Prabhakar A, Chen DH, Petrov AN, Puglisi JD. Wang J, et al. Among authors: lapointe cp. Nature. 2019 Sep;573(7775):605-608. doi: 10.1038/s41586-019-1561-0. Epub 2019 Sep 18. Nature. 2019. PMID: 31534220 Free PMC article.
A memory of eS25 loss drives resistance phenotypes.
Johnson AG, Flynn RA, Lapointe CP, Ooi YS, Zhao ML, Richards CM, Qiao W, Yamada SB, Couthouis J, Gitler AD, Carette JE, Puglisi JD. Johnson AG, et al. Among authors: lapointe cp. Nucleic Acids Res. 2020 Jul 27;48(13):7279-7297. doi: 10.1093/nar/gkaa444. Nucleic Acids Res. 2020. PMID: 32463448 Free PMC article.
Universal features of Nsp1-mediated translational shutdown by coronaviruses.
Schubert K, Karousis ED, Ban I, Lapointe CP, Leibundgut M, Bäumlin E, Kummerant E, Scaiola A, Schönhut T, Ziegelmüller J, Puglisi JD, Mühlemann O, Ban N. Schubert K, et al. Among authors: lapointe cp. Mol Cell. 2023 Oct 5;83(19):3546-3557.e8. doi: 10.1016/j.molcel.2023.09.002. Mol Cell. 2023. PMID: 37802027
Unbiased screen of RNA tailing activities reveals a poly(UG) polymerase.
Preston MA, Porter DF, Chen F, Buter N, Lapointe CP, Keles S, Kimble J, Wickens M. Preston MA, et al. Among authors: lapointe cp. Nat Methods. 2019 May;16(5):437-445. doi: 10.1038/s41592-019-0370-6. Epub 2019 Apr 15. Nat Methods. 2019. PMID: 30988468 Free PMC article.
25 results