Chen QY - Search Results

1

Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.

Pohl MO, Martin-Sancho L, Ratnayake R, White KM, Riva L, Chen QY, Lieber G, Busnadiego I, Yin X, Lin S, Pu Y, Pache L, Rosales R, Déjosez M, Qin Y, De Jesus PD, Beall A, Yoh S, Hale BG, Zwaka TP, Matsunaga N, García-Sastre A, Stertz S, Chanda SK, Luesch H. Pohl MO, et al. Among authors: chen qy. ACS Infect Dis. 2022 Jul 8;8(7):1265-1279. doi: 10.1021/acsinfecdis.2c00008. Epub 2022 Jun 29. ACS Infect Dis. 2022. PMID: 35766385 Free PMC article.

2

Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity.

Chen QY, Liu Y, Luesch H. Chen QY, et al. ACS Med Chem Lett. 2011 Nov 10;2(11):861-865. doi: 10.1021/ml200176m. Epub 2011 Aug 31. ACS Med Chem Lett. 2011. PMID: 22081789 Free PMC article.

3

Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity.

Chen QY, Liu Y, Cai W, Luesch H. Chen QY, et al. J Med Chem. 2014 Apr 10;57(7):3011-29. doi: 10.1021/jm4019965. Epub 2014 Mar 24. J Med Chem. 2014. PMID: 24660812 Free PMC article.

4

Evaluation of class I HDAC isoform selectivity of largazole analogues.

Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Kim B, et al. Among authors: chen qy. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3728-31. doi: 10.1016/j.bmcl.2014.07.006. Epub 2014 Jul 9. Bioorg Med Chem Lett. 2014. PMID: 25070421 Free PMC article.

5

Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.

Salvador LA, Park H, Al-Awadhi FH, Liu Y, Kim B, Zeller SL, Chen QY, Hong J, Luesch H. Salvador LA, et al. Among authors: chen qy. ACS Med Chem Lett. 2014 Jul 7;5(8):905-10. doi: 10.1021/ml500170r. eCollection 2014 Aug 14. ACS Med Chem Lett. 2014. PMID: 25147612 Free PMC article.

6

Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases.

Luo D, Chen QY, Luesch H. Luo D, et al. Among authors: chen qy. J Org Chem. 2016 Jan 15;81(2):532-44. doi: 10.1021/acs.joc.5b02386. Epub 2015 Dec 28. J Org Chem. 2016. PMID: 26709602 Free PMC article.

7

Total Synthesis and Biological Evaluation of Apratoxin E and Its C30 Epimer: Configurational Reassignment of the Natural Product.

Wu P, Cai W, Chen QY, Xu S, Yin R, Li Y, Zhang W, Luesch H. Wu P, et al. Among authors: chen qy. Org Lett. 2016 Oct 21;18(20):5400-5403. doi: 10.1021/acs.orglett.6b02780. Epub 2016 Oct 10. Org Lett. 2016. PMID: 27723359 Free PMC article.

8

Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.

Cai W, Chen QY, Dang LH, Luesch H. Cai W, et al. Among authors: chen qy. ACS Med Chem Lett. 2017 Sep 18;8(10):1007-1012. doi: 10.1021/acsmedchemlett.7b00192. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057042 Free PMC article.

9

Apratyramide, a Marine-Derived Peptidic Stimulator of VEGF-A and Other Growth Factors with Potential Application in Wound Healing.

Cai W, Salvador-Reyes LA, Zhang W, Chen QY, Matthew S, Ratnayake R, Seo SJ, Dolles S, Gibson DJ, Paul VJ, Luesch H. Cai W, et al. Among authors: chen qy. ACS Chem Biol. 2018 Jan 19;13(1):91-99. doi: 10.1021/acschembio.7b00827. Epub 2017 Dec 5. ACS Chem Biol. 2018. PMID: 29205032 Free PMC article.

10

Correction to "Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors".

Cai W, Chen QY, Dang LH, Luesch H. Cai W, et al. Among authors: chen qy. ACS Med Chem Lett. 2017 Dec 7;8(12):1342. doi: 10.1021/acsmedchemlett.7b00498. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29266134 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

1,113 results

Search Page