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Sec61 Inhibitor Apratoxin S4 Potently Inhibits SARS-CoV-2 and Exhibits Broad-Spectrum Antiviral Activity.
Pohl MO, Martin-Sancho L, Ratnayake R, White KM, Riva L, Chen QY, Lieber G, Busnadiego I, Yin X, Lin S, Pu Y, Pache L, Rosales R, Déjosez M, Qin Y, De Jesus PD, Beall A, Yoh S, Hale BG, Zwaka TP, Matsunaga N, García-Sastre A, Stertz S, Chanda SK, Luesch H. Pohl MO, et al. Among authors: yoh s. ACS Infect Dis. 2022 Jul 8;8(7):1265-1279. doi: 10.1021/acsinfecdis.2c00008. Epub 2022 Jun 29. ACS Infect Dis. 2022. PMID: 35766385 Free PMC article.
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells.
Yin X, Riva L, Pu Y, Martin-Sancho L, Kanamune J, Yamamoto Y, Sakai K, Gotoh S, Miorin L, De Jesus PD, Yang CC, Herbert KM, Yoh S, Hultquist JF, García-Sastre A, Chanda SK. Yin X, et al. Among authors: yoh s. Cell Rep. 2021 Jan 12;34(2):108628. doi: 10.1016/j.celrep.2020.108628. Cell Rep. 2021. PMID: 33440148 Free PMC article.
Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation.
Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VR, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK. Soonthornvacharin S, et al. Among authors: yoh sm. Nat Microbiol. 2017 Mar 1;2:17022. doi: 10.1038/nmicrobiol.2017.22. Nat Microbiol. 2017. PMID: 28248290 Free PMC article.
Sensor Sensibility-HIV-1 and the Innate Immune Response.
Yin X, Langer S, Zhang Z, Herbert KM, Yoh S, König R, Chanda SK. Yin X, et al. Among authors: yoh s. Cells. 2020 Jan 20;9(1):254. doi: 10.3390/cells9010254. Cells. 2020. PMID: 31968566 Free PMC article. Review.
Recognition of HIV-1 capsid by PQBP1 licenses an innate immune sensing of nascent HIV-1 DNA.
Yoh SM, Mamede JI, Lau D, Ahn N, Sánchez-Aparicio MT, Temple J, Tuckwell A, Fuchs NV, Cianci GC, Riva L, Curry H, Yin X, Gambut S, Simons LM, Hultquist JF, König R, Xiong Y, García-Sastre A, Böcking T, Hope TJ, Chanda SK. Yoh SM, et al. Mol Cell. 2022 Aug 4;82(15):2871-2884.e6. doi: 10.1016/j.molcel.2022.06.010. Epub 2022 Jul 8. Mol Cell. 2022. PMID: 35809572 Free PMC article.
PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.
Yoh SM, Schneider M, Seifried J, Soonthornvacharin S, Akleh RE, Olivieri KC, De Jesus PD, Ruan C, de Castro E, Ruiz PA, Germanaud D, des Portes V, García-Sastre A, König R, Chanda SK. Yoh SM, et al. Cell. 2015 Jun 4;161(6):1293-1305. doi: 10.1016/j.cell.2015.04.050. Cell. 2015. PMID: 26046437 Free PMC article.
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.
Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. Guo H, et al. Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001. Cell Host Microbe. 2016. PMID: 27078069 Free PMC article.
The multi-tasking P-TEFb complex.
Brès V, Yoh SM, Jones KA. Brès V, et al. Curr Opin Cell Biol. 2008 Jun;20(3):334-40. doi: 10.1016/j.ceb.2008.04.008. Epub 2008 May 29. Curr Opin Cell Biol. 2008. PMID: 18513937 Free PMC article. Review.
57 results