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Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis.
Levasseur EM, Yamada K, Piñeros AR, Wu W, Syed F, Orr KS, Anderson-Baucum E, Mastracci TL, Maier B, Mosley AL, Liu Y, Bernal-Mizrachi E, Alonso LC, Scott D, Garcia-Ocaña A, Tersey SA, Mirmira RG. Levasseur EM, et al. Among authors: wu w. Sci Signal. 2019 Dec 3;12(610):eaax0715. doi: 10.1126/scisignal.aax0715. Sci Signal. 2019. PMID: 31796630 Free PMC article.
Deoxyhypusine synthase promotes a pro-inflammatory macrophage phenotype.
Anderson-Baucum E, Piñeros AR, Kulkarni A, Webb-Robertson BJ, Maier B, Anderson RM, Wu W, Tersey SA, Mastracci TL, Casimiro I, Scheuner D, Metz TO, Nakayasu ES, Evans-Molina C, Mirmira RG. Anderson-Baucum E, et al. Among authors: wu w. Cell Metab. 2021 Sep 7;33(9):1883-1893.e7. doi: 10.1016/j.cmet.2021.08.003. Cell Metab. 2021. PMID: 34496231 Free PMC article.
Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19.
Kusmartseva I, Wu W, Syed F, Van Der Heide V, Jorgensen M, Joseph P, Tang X, Candelario-Jalil E, Yang C, Nick H, Harbert JL, Posgai AL, Paulsen JD, Lloyd R, Cechin S, Pugliese A, Campbell-Thompson M, Vander Heide RS, Evans-Molina C, Homann D, Atkinson MA. Kusmartseva I, et al. Among authors: wu w. Cell Metab. 2020 Dec 1;32(6):1041-1051.e6. doi: 10.1016/j.cmet.2020.11.005. Epub 2020 Nov 13. Cell Metab. 2020. PMID: 33207244 Free PMC article.
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