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Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder.
Zeng Y, Navarro P, Shirali M, Howard DM, Adams MJ, Hall LS, Clarke TK, Thomson PA, Smith BH, Murray A, Padmanabhan S, Hayward C, Boutin T, MacIntyre DJ, Lewis CM, Wray NR, Mehta D, Penninx BWJH, Milaneschi Y, Baune BT, Air T, Hottenga JJ, Mbarek H, Castelao E, Pistis G, Schulze TG, Streit F, Forstner AJ, Byrne EM, Martin NG, Breen G, Müller-Myhsok B, Lucae S, Kloiber S, Domenici E; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Deary IJ, Porteous DJ, Haley CS, McIntosh AM. Zeng Y, et al. Among authors: howard dm. Biol Psychiatry. 2017 Sep 1;82(5):312-321. doi: 10.1016/j.biopsych.2016.12.012. Epub 2016 Dec 16. Biol Psychiatry. 2017. PMID: 28153336 Free PMC article.
Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.
Hall LS, Adams MJ, Arnau-Soler A, Clarke TK, Howard DM, Zeng Y, Davies G, Hagenaars SP, Maria Fernandez-Pujals A, Gibson J, Wigmore EM, Boutin TS, Hayward C, Scotland G; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Porteous DJ, Deary IJ, Thomson PA, Haley CS, McIntosh AM. Hall LS, et al. Among authors: howard dm. Transl Psychiatry. 2018 Jan 10;8(1):9. doi: 10.1038/s41398-017-0034-1. Transl Psychiatry. 2018. PMID: 29317602 Free PMC article.
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression.
Strawbridge RJ, Ward J, Lyall LM, Tunbridge EM, Cullen B, Graham N, Ferguson A, Johnston KJA, Lyall DM, Mackay D, Cavanagh J, Howard DM, Adams MJ, Deary I, Escott-Price V, O'Donovan M, McIntosh AM, Bailey MES, Pell JP, Harrison PJ, Smith DJ. Strawbridge RJ, et al. Among authors: howard dm. Transl Psychiatry. 2018 Sep 4;8(1):178. doi: 10.1038/s41398-018-0236-1. Transl Psychiatry. 2018. PMID: 30181555 Free PMC article.
Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
Sanchez-Roige S, Palmer AA, Fontanillas P, Elson SL; 23andMe Research Team, the Substance Use Disorder Working Group of the Psychiatric Genomics Consortium; Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary IJ, McIntosh AM, Clarke TK. Sanchez-Roige S, et al. Among authors: howard dm. Am J Psychiatry. 2019 Feb 1;176(2):107-118. doi: 10.1176/appi.ajp.2018.18040369. Epub 2018 Oct 19. Am J Psychiatry. 2019. PMID: 30336701 Free PMC article.
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.
Amare AT, Vaez A, Hsu YH, Direk N, Kamali Z, Howard DM, McIntosh AM, Tiemeier H, Bültmann U, Snieder H, Hartman CA. Amare AT, et al. Among authors: howard dm. Mol Psychiatry. 2020 Jul;25(7):1420-1429. doi: 10.1038/s41380-018-0336-6. Epub 2019 Jan 9. Mol Psychiatry. 2020. PMID: 30626913 Free PMC article.
Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder.
Trzaskowski M, Mehta D, Peyrot WJ, Hawkes D, Davies D, Howard DM, Kemper KE, Sidorenko J, Maier R, Ripke S, Mattheisen M, Baune BT, Grabe HJ, Heath AC, Jones L, Jones I, Madden PAF, McIntosh AM, Breen G, Lewis CM, Børglum AD, Sullivan PF, Martin NG, Kendler KS, Levinson DF, Wray NR; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Trzaskowski M, et al. Among authors: howard dm. Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):439-447. doi: 10.1002/ajmg.b.32713. Epub 2019 Feb 1. Am J Med Genet B Neuropsychiatr Genet. 2019. PMID: 30708398 Free PMC article.
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.
Howard DM, Adams MJ, Clarke TK, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA; 23andMe Research Team; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Trzaskowski M, Byrne EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Howard DM, et al. Nat Neurosci. 2019 Mar;22(3):343-352. doi: 10.1038/s41593-018-0326-7. Epub 2019 Feb 4. Nat Neurosci. 2019. PMID: 30718901 Free PMC article.
Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank.
Neilson E, Shen X, Cox SR, Clarke TK, Wigmore EM, Gibson J, Howard DM, Adams MJ, Harris MA, Davies G, Deary IJ, Whalley HC, McIntosh AM, Lawrie SM. Neilson E, et al. Among authors: howard dm. Biol Psychiatry. 2019 Oct 1;86(7):536-544. doi: 10.1016/j.biopsych.2019.04.013. Epub 2019 Apr 22. Biol Psychiatry. 2019. PMID: 31171358
143 results