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Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson NA, Latorre-Crespo E, Terradas-Terradas M, Lemos-Portela J, Purcell AC, Livesey BJ, Hillary RF, Murphy L, Fawkes A, MacGillivray L, Copland M, Marioni RE, Marsh JA, Harris SE, Cox SR, Deary IJ, Schumacher LJ, Kirschner K, Chandra T. Robertson NA, et al. Among authors: kirschner k. Nat Med. 2022 Jul;28(7):1439-1446. doi: 10.1038/s41591-022-01883-3. Epub 2022 Jul 4. Nat Med. 2022. PMID: 35788175 Free PMC article.
Chromosome organisation during ageing and senescence.
Chandra T, Kirschner K. Chandra T, et al. Among authors: kirschner k. Curr Opin Cell Biol. 2016 Jun;40:161-167. doi: 10.1016/j.ceb.2016.03.020. Epub 2016 Apr 19. Curr Opin Cell Biol. 2016. PMID: 27101466 Free article. Review.
SC3: consensus clustering of single-cell RNA-seq data.
Kiselev VY, Kirschner K, Schaub MT, Andrews T, Yiu A, Chandra T, Natarajan KN, Reik W, Barahona M, Green AR, Hemberg M. Kiselev VY, et al. Among authors: kirschner k. Nat Methods. 2017 May;14(5):483-486. doi: 10.1038/nmeth.4236. Epub 2017 Mar 27. Nat Methods. 2017. PMID: 28346451 Free PMC article.
Experimental design for single-cell RNA sequencing.
Baran-Gale J, Chandra T, Kirschner K. Baran-Gale J, et al. Among authors: kirschner k. Brief Funct Genomics. 2018 Jul 1;17(4):233-239. doi: 10.1093/bfgp/elx035. Brief Funct Genomics. 2018. PMID: 29126257 Free PMC article. Review.
Notch Signaling Mediates Secondary Senescence.
Teo YV, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, Kiourtis C, Müller M, Green AR, Adams PD, Acosta JC, Bird TG, Kirschner K, Neretti N, Chandra T. Teo YV, et al. Among authors: kirschner k. Cell Rep. 2019 Apr 23;27(4):997-1007.e5. doi: 10.1016/j.celrep.2019.03.104. Cell Rep. 2019. PMID: 31018144 Free PMC article.
Age-related clonal haemopoiesis is associated with increased epigenetic age.
Robertson NA, Hillary RF, McCartney DL, Terradas-Terradas M, Higham J, Sproul D, Deary IJ, Kirschner K, Marioni RE, Chandra T. Robertson NA, et al. Among authors: kirschner k. Curr Biol. 2019 Aug 19;29(16):R786-R787. doi: 10.1016/j.cub.2019.07.011. Curr Biol. 2019. PMID: 31430471 Free article.
Functional heterogeneity in senescence.
Kirschner K, Rattanavirotkul N, Quince MF, Chandra T. Kirschner K, et al. Biochem Soc Trans. 2020 Jun 30;48(3):765-773. doi: 10.1042/BST20190109. Biochem Soc Trans. 2020. PMID: 32369550 Free PMC article. Review.
Clonality in haematopoietic stem cell ageing.
Terradas-Terradas M, Robertson NA, Chandra T, Kirschner K. Terradas-Terradas M, et al. Among authors: kirschner k. Mech Ageing Dev. 2020 Jul;189:111279. doi: 10.1016/j.mad.2020.111279. Epub 2020 Jun 8. Mech Ageing Dev. 2020. PMID: 32526214 Free PMC article. Review.
319 results