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Page 1
Safety, recommended dose, efficacy and immune correlates for nintedanib in combination with pembrolizumab in patients with advanced cancers.
Baldini C, Danlos FX, Varga A, Texier M, Halse H, Mouraud S, Cassard L, Champiat S, Signolle N, Vuagnat P, Martin-Romano P, Michot JM, Bahleda R, Gazzah A, Boselli L, Bredel D, Grivel J, Mohamed-Djalim C, Escriou G, Grynszpan L, Bigorgne A, Rafie S, Abbassi A, Ribrag V, Postel-Vinay S, Hollebecque A, Susini S, Farhane S, Lacroix L, Parpaleix A, Laghouati S, Zitvogel L, Adam J, Chaput N, Soria JC, Massard C, Marabelle A. Baldini C, et al. Among authors: parpaleix a. J Exp Clin Cancer Res. 2022 Jul 7;41(1):217. doi: 10.1186/s13046-022-02423-0. J Exp Clin Cancer Res. 2022. PMID: 35794623 Free PMC article. Clinical Trial.
Osteopontin, a Key Mediator Expressed by Senescent Pulmonary Vascular Cells in Pulmonary Hypertension.
Saker M, Lipskaia L, Marcos E, Abid S, Parpaleix A, Houssaini A, Validire P, Girard P, Noureddine H, Boyer L, Vienney N, Amsellem V, Marguerit L, Maitre B, Derumeaux G, Dubois-Rande JL, Jourdan-Lesaux C, Delcroix M, Quarck R, Adnot S. Saker M, et al. Among authors: parpaleix a. Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1879-90. doi: 10.1161/ATVBAHA.116.307839. Epub 2016 Jul 21. Arterioscler Thromb Vasc Biol. 2016. PMID: 27444202
Impaired humoral and cellular immune responses to influenza vaccination in chronic obstructive pulmonary disease patients.
Parpaleix A, Boyer L, Wiedemann A, Lacabaratz C, Margarit L, Enouf V, Le Corvoisier P, Lino A, Covali-Noroc A, Housset B, Chouaid C, Maitre B, Lévy Y, Lelièvre JD, Adnot S. Parpaleix A, et al. J Allergy Clin Immunol. 2017 Dec;140(6):1754-1757.e6. doi: 10.1016/j.jaci.2017.07.038. Epub 2017 Sep 7. J Allergy Clin Immunol. 2017. PMID: 28889955 No abstract available.
CCR5 as a treatment target in pulmonary arterial hypertension.
Amsellem V, Lipskaia L, Abid S, Poupel L, Houssaini A, Quarck R, Marcos E, Mouraret N, Parpaleix A, Bobe R, Gary-Bobo G, Saker M, Dubois-Randé JL, Gladwin MT, Norris KA, Delcroix M, Combadière C, Adnot S. Amsellem V, et al. Among authors: parpaleix a. Circulation. 2014 Sep 9;130(11):880-891. doi: 10.1161/CIRCULATIONAHA.114.010757. Epub 2014 Jul 3. Circulation. 2014. PMID: 24993099 Free PMC article.
Extracellular Calpain/Calpastatin Balance Is Involved in the Progression of Pulmonary Hypertension.
Wan F, Letavernier E, Abid S, Houssaini A, Czibik G, Marcos E, Rideau D, Parpaleix A, Lipskaia L, Amsellem V, Gellen B, Sawaki D, Derumeaux G, Dubois-Randé JL, Delcroix M, Quarck R, Baud L, Adnot S. Wan F, et al. Among authors: parpaleix a. Am J Respir Cell Mol Biol. 2016 Sep;55(3):337-51. doi: 10.1165/rcmb.2015-0257OC. Am J Respir Cell Mol Biol. 2016. PMID: 26974350
Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.
Houssaini A, Abid S, Derumeaux G, Wan F, Parpaleix A, Rideau D, Marcos E, Kebe K, Czibik G, Sawaki D, Treins C, Dubois-Randé JL, Li Z, Amsellem V, Lipskaia L, Pende M, Adnot S. Houssaini A, et al. Among authors: parpaleix a. Am J Respir Cell Mol Biol. 2016 Sep;55(3):352-67. doi: 10.1165/rcmb.2015-0339OC. Am J Respir Cell Mol Biol. 2016. PMID: 26991739
mTOR pathway activation drives lung cell senescence and emphysema.
Houssaini A, Breau M, Kebe K, Abid S, Marcos E, Lipskaia L, Rideau D, Parpaleix A, Huang J, Amsellem V, Vienney N, Validire P, Maitre B, Attwe A, Lukas C, Vindrieux D, Boczkowski J, Derumeaux G, Pende M, Bernard D, Meiners S, Adnot S. Houssaini A, et al. Among authors: parpaleix a. JCI Insight. 2018 Feb 8;3(3):e93203. doi: 10.1172/jci.insight.93203. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415880 Free PMC article.
New Nitric Oxide Donor NCX 1443: Therapeutic Effects on Pulmonary Hypertension in the SAD Mouse Model of Sickle Cell Disease.
Abid S, Kebe K, Houssaïni A, Tomberli F, Marcos E, Bizard E, Breau M, Parpaleix A, Tissot CM, Maitre B, Lipskaia L, Derumeaux G, Bastia E, Mekontso-Dessap A, Adnot S. Abid S, et al. Among authors: parpaleix a. J Cardiovasc Pharmacol. 2018 May;71(5):283-292. doi: 10.1097/FJC.0000000000000570. J Cardiovasc Pharmacol. 2018. PMID: 29438213
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