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Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein.
Yang Z, Loy J, Poirson B, Dai Y, Rajendran S, Xu S, Spires V, Gururajan M, Lin Z, Arbanas J, Carl S, Pace S, Wang Y, Mehl J, Vasudevan K, Spires T, Novosiadly R, Coker S, Perez R, Covello K, Morin P, Graziano R, Broz M, Lehman-McKeeman L. Yang Z, et al. Among authors: pace s. Front Pharmacol. 2022 Jun 20;13:829063. doi: 10.3389/fphar.2022.829063. eCollection 2022. Front Pharmacol. 2022. PMID: 35795558 Free PMC article.
Target-Mediated Drug Disposition Affects the Pharmacokinetics of Interleukin-10 Fragment Crystallizable Fusion Proteins at Pharmacologically Active Doses.
Yang Z, Rajendran S, Spires V, Poirson B, Gururajan M, Lin Z, Arbanas J, Krystek S, Loy J, Cheng Y, Carl S, Pace S, Wang Y, Mehl J, Xu S, Vasudevan K, Broz M, Lehman-McKeeman L, Morin P, Graziano RF. Yang Z, et al. Among authors: pace s. Drug Metab Dispos. 2022 Jul;50(7):898-908. doi: 10.1124/dmd.121.000799. Epub 2022 May 11. Drug Metab Dispos. 2022. PMID: 35545256
Meeting statement: Call to action for step-change in health behaviours.
Bach Habersaat K, Koylyu A, Likki T, Fietje N, Scherzer M, Snijders V, Mazhnaia A, Roy S, Berisha M, Basholli FM, Catic S, Nagyova I, Sivelä J, Cirulli F, Van der Biest L, Baros S, Lagarija ŠC, Schilling M, Nohlen HU, Forjaz MJ, Romay-Barja M, Üçüncü İ, Flaschberger E, Nikolić TK, Nesterova O, Lukmine I, Rivero-Montesdeoca Y, Loss J, Andreasyan D, Oikonomou MC, Godoy-Ramirez K, Karregård S, Murphy R, Niskanovic J, Van Brussel L, Telo de Arriaga M, Wojtyniak B, Price C, Altymysheva N, Jost KS, Berjaoui R, Saaristo P, Glazewska J, Topuridze M, Craig B, Mukhtarova P, Duishenkulova M, Pace S, MacLennan M, Bachanovikj M, Jakubowski E, Zeroug-Vial H, Gould A, Cutler A, Leurs M, Silitrari N, Bratu EC, Young J, Bianco VM, Butler R. Bach Habersaat K, et al. Among authors: pace s. Public Health Pract (Oxf). 2024 Apr 25;7:100498. doi: 10.1016/j.puhip.2024.100498. eCollection 2024 Jun. Public Health Pract (Oxf). 2024. PMID: 38779506 Free PMC article.
356 results