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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Gödel M, Hartleben B, Herbach N, Liu S, Zschiedrich S, Lu S, Debreczeni-Mór A, Lindenmeyer MT, Rastaldi MP, Hartleben G, Wiech T, Fornoni A, Nelson RG, Kretzler M, Wanke R, Pavenstädt H, Kerjaschki D, Cohen CD, Hall MN, Rüegg MA, Inoki K, Walz G, Huber TB. Gödel M, et al. Among authors: walz g. J Clin Invest. 2011 Jun;121(6):2197-209. doi: 10.1172/JCI44774. Epub 2011 May 23. J Clin Invest. 2011. PMID: 21606591 Free PMC article.
aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.
Hartleben B, Widmeier E, Suhm M, Worthmann K, Schell C, Helmstädter M, Wiech T, Walz G, Leitges M, Schiffer M, Huber TB. Hartleben B, et al. Among authors: walz g. J Am Soc Nephrol. 2013 Feb;24(2):253-67. doi: 10.1681/ASN.2012060582. Epub 2013 Jan 18. J Am Soc Nephrol. 2013. PMID: 23334392 Free PMC article.
N-wasp is required for stabilization of podocyte foot processes.
Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB. Schell C, et al. Among authors: walz g. J Am Soc Nephrol. 2013 Apr;24(5):713-21. doi: 10.1681/ASN.2012080844. Epub 2013 Mar 7. J Am Soc Nephrol. 2013. PMID: 23471198 Free PMC article.
Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis.
Bechtel W, Helmstädter M, Balica J, Hartleben B, Kiefer B, Hrnjic F, Schell C, Kretz O, Liu S, Geist F, Kerjaschki D, Walz G, Huber TB. Bechtel W, et al. Among authors: walz g. J Am Soc Nephrol. 2013 Apr;24(5):727-43. doi: 10.1681/ASN.2012070700. Epub 2013 Mar 14. J Am Soc Nephrol. 2013. PMID: 23492732 Free PMC article.
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS. Hoff S, et al. Among authors: walz g. Nat Genet. 2013 Aug;45(8):951-6. doi: 10.1038/ng.2681. Epub 2013 Jun 23. Nat Genet. 2013. PMID: 23793029 Free PMC article.
Targeting mTOR Signaling Can Prevent the Progression of FSGS.
Zschiedrich S, Bork T, Liang W, Wanner N, Eulenbruch K, Munder S, Hartleben B, Kretz O, Gerber S, Simons M, Viau A, Burtin M, Wei C, Reiser J, Herbach N, Rastaldi MP, Cohen CD, Tharaux PL, Terzi F, Walz G, Gödel M, Huber TB. Zschiedrich S, et al. Among authors: walz g. J Am Soc Nephrol. 2017 Jul;28(7):2144-2157. doi: 10.1681/ASN.2016050519. Epub 2017 Mar 7. J Am Soc Nephrol. 2017. PMID: 28270414 Free PMC article.
298 results