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Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities.
Mallard TT, Linnér RK, Grotzinger AD, Sanchez-Roige S, Seidlitz J, Okbay A, de Vlaming R, Meddens SFW; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Palmer AA, Davis LK, Tucker-Drob EM, Kendler KS, Keller MC, Koellinger PD, Harden KP. Mallard TT, et al. Cell Genom. 2022 Jun 8;2(6):100140. doi: 10.1016/j.xgen.2022.100140. Epub 2022 Jun 8. Cell Genom. 2022. PMID: 35812988 Free PMC article.
Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits.
Grotzinger AD, Rhemtulla M, de Vlaming R, Ritchie SJ, Mallard TT, Hill WD, Ip HF, Marioni RE, McIntosh AM, Deary IJ, Koellinger PD, Harden KP, Nivard MG, Tucker-Drob EM. Grotzinger AD, et al. Among authors: mallard tt. Nat Hum Behav. 2019 May;3(5):513-525. doi: 10.1038/s41562-019-0566-x. Epub 2019 Apr 8. Nat Hum Behav. 2019. PMID: 30962613 Free PMC article.
Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.
Demange PA, Malanchini M, Mallard TT, Biroli P, Cox SR, Grotzinger AD, Tucker-Drob EM, Abdellaoui A, Arseneault L, van Bergen E, Boomsma DI, Caspi A, Corcoran DL, Domingue BW, Harris KM, Ip HF, Mitchell C, Moffitt TE, Poulton R, Prinz JA, Sugden K, Wertz J, Williams BS, de Zeeuw EL, Belsky DW, Harden KP, Nivard MG. Demange PA, et al. Among authors: mallard tt. Nat Genet. 2021 Jan;53(1):35-44. doi: 10.1038/s41588-020-00754-2. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414549 Free PMC article.
Morphological integration of the human brain across adolescence and adulthood.
Nadig A, Seidlitz J, McDermott CL, Liu S, Bethlehem R, Moore TM, Mallard TT, Clasen LS, Blumenthal JD, Lalonde F, Gur RC, Gur RE, Bullmore ET, Satterthwaite TD, Raznahan A. Nadig A, et al. Among authors: mallard tt. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2023860118. doi: 10.1073/pnas.2023860118. Proc Natl Acad Sci U S A. 2021. PMID: 33811142 Free PMC article.
Item-Level Genome-Wide Association Study of the Alcohol Use Disorders Identification Test in Three Population-Based Cohorts.
Mallard TT, Savage JE, Johnson EC, Huang Y, Edwards AC, Hottenga JJ, Grotzinger AD, Gustavson DE, Jennings MV, Anokhin A, Dick DM, Edenberg HJ, Kramer JR, Lai D, Meyers JL, Pandey AK, Harden KP, Nivard MG, de Geus EJC, Boomsma DI, Agrawal A, Davis LK, Clarke TK, Palmer AA, Sanchez-Roige S. Mallard TT, et al. Am J Psychiatry. 2022 Jan;179(1):58-70. doi: 10.1176/appi.ajp.2020.20091390. Epub 2021 May 14. Am J Psychiatry. 2022. PMID: 33985350 Free PMC article.
Mapping Pathways by Which Genetic Risk Influences Adolescent Externalizing Behavior: The Interplay Between Externalizing Polygenic Risk Scores, Parental Knowledge, and Peer Substance Use.
Kuo SI, Salvatore JE, Barr PB, Aliev F, Anokhin A, Bucholz KK, Chan G, Edenberg HJ, Hesselbrock V, Kamarajan C, Kramer JR, Lai D, Mallard TT, Nurnberger JI Jr, Pandey G, Plawecki MH, Sanchez-Roige S, Waldman I, Palmer AA; Externalizing Consortium; Dick DM. Kuo SI, et al. Among authors: mallard tt. Behav Genet. 2021 Sep;51(5):543-558. doi: 10.1007/s10519-021-10067-7. Epub 2021 Jun 12. Behav Genet. 2021. PMID: 34117972 Free PMC article.
Resource profile and user guide of the Polygenic Index Repository.
Becker J, Burik CAP, Goldman G, Wang N, Jayashankar H, Bennett M, Belsky DW, Karlsson Linnér R, Ahlskog R, Kleinman A, Hinds DA; 23andMe Research Group; Caspi A, Corcoran DL, Moffitt TE, Poulton R, Sugden K, Williams BS, Harris KM, Steptoe A, Ajnakina O, Milani L, Esko T, Iacono WG, McGue M, Magnusson PKE, Mallard TT, Harden KP, Tucker-Drob EM, Herd P, Freese J, Young A, Beauchamp JP, Koellinger PD, Oskarsson S, Johannesson M, Visscher PM, Meyer MN, Laibson D, Cesarini D, Benjamin DJ, Turley P, Okbay A. Becker J, et al. Among authors: mallard tt. Nat Hum Behav. 2021 Dec;5(12):1744-1758. doi: 10.1038/s41562-021-01119-3. Epub 2021 Jun 17. Nat Hum Behav. 2021. PMID: 34140656 Free PMC article.
55 results