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Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure.
Ma J, Guillot A, Yang Z, Mackowiak B, Hwang S, Park O, Peiffer BJ, Ahmadi AR, Melo L, Kusumanchi P, Huda N, Saxena R, He Y, Guan Y, Feng D, Sancho-Bru P, Zang M, Cameron AM, Bataller R, Tacke F, Sun Z, Liangpunsakul S, Gao B. Ma J, et al. Among authors: saxena r. J Clin Invest. 2022 Jul 15;132(14):e157780. doi: 10.1172/JCI157780. J Clin Invest. 2022. PMID: 35838051 Free PMC article.
Effects of Age, Sex, Body Weight, and Quantity of Alcohol Consumption on Occurrence and Severity of Alcoholic Hepatitis.
Liangpunsakul S, Puri P, Shah VH, Kamath P, Sanyal A, Urban T, Ren X, Katz B, Radaeva S, Chalasani N, Crabb DW; Translational Research and Evolving Alcoholic Hepatitis Treatment Consortium. Liangpunsakul S, et al. Clin Gastroenterol Hepatol. 2016 Dec;14(12):1831-1838.e3. doi: 10.1016/j.cgh.2016.05.041. Epub 2016 Jun 15. Clin Gastroenterol Hepatol. 2016. PMID: 27320325 Free PMC article.
Acute Alcoholic Hepatitis: Natural History and Predictors of Mortality Using a Multicenter Prospective Study.
Lourens S, Sunjaya DB, Singal A, Liangpunsakul S, Puri P, Sanyal A, Ren X, Gores GJ, Radaeva S, Chalasani N, Crabb DW, Katz B, Kamath PS, Shah VH; TREAT Consortium. Lourens S, et al. Mayo Clin Proc Innov Qual Outcomes. 2017 Apr 28;1(1):37-48. doi: 10.1016/j.mayocpiqo.2017.04.004. eCollection 2017 Jul. Mayo Clin Proc Innov Qual Outcomes. 2017. PMID: 30225400 Free PMC article.
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC).
Zhou T, Kyritsi K, Wu N, Francis H, Yang Z, Chen L, O'Brien A, Kennedy L, Ceci L, Meadows V, Kusumanchi P, Wu C, Baiocchi L, Skill NJ, Saxena R, Sybenga A, Xie L, Liangpunsakul S, Meng F, Alpini G, Glaser S. Zhou T, et al. Among authors: saxena r. EBioMedicine. 2019 Oct;48:130-142. doi: 10.1016/j.ebiom.2019.09.013. Epub 2019 Sep 12. EBioMedicine. 2019. PMID: 31522982 Free PMC article.
Hepatic Histopathology Among Excessive Drinkers Without Advanced Liver Disease.
Chang B, Huang A, Saxena R, Sun Y, Liu S, Zhou G, Li B, Teng G, Zhao J, Zhang W, Jiang Y, Han S, Yang Z, Zhao J, Zou Z, Liangpunsakul S. Chang B, et al. Among authors: saxena r. Alcohol Alcohol. 2021 Oct 29;56(6):669-677. doi: 10.1093/alcalc/agab017. Alcohol Alcohol. 2021. PMID: 33765150 Free PMC article.
Corticosteroid plus glycyrrhizin therapy for chronic drug- or herb-induced liver injury achieves biochemical and histological improvements: a randomised open-label trial.
Wang JB, Huang A, Wang Y, Ji D, Liang QS, Zhao J, Zhou G, Liu S, Niu M, Sun Y, Tian H, Teng GJ, Chang BX, Bi JF, Peng XX, Xin S, Xie H, Ma X, Mao YM, Liangpunsakul S, Saxena R, Aithal GP, Xiao XH, Zhao J, Zou Z. Wang JB, et al. Among authors: saxena r. Aliment Pharmacol Ther. 2022 May;55(10):1297-1310. doi: 10.1111/apt.16902. Epub 2022 Mar 31. Aliment Pharmacol Ther. 2022. PMID: 35362188 Clinical Trial.
2,488 results