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Aging alters antiviral signaling pathways resulting in functional impairment in innate immunity in response to pattern recognition receptor agonists.
Connors J, Taramangalam B, Cusimano G, Bell MR, Matt SM, Runner K, Gaskill PJ, DeFilippis V, Nikolich-Žugich J, Kutzler MA, Haddad EK. Connors J, et al. Among authors: kutzler ma. Geroscience. 2022 Oct;44(5):2555-2572. doi: 10.1007/s11357-022-00612-5. Epub 2022 Jul 18. Geroscience. 2022. PMID: 35849213 Free PMC article.
The 2020 Pandemic: Current SARS-CoV-2 Vaccine Development.
Alturki SO, Alturki SO, Connors J, Cusimano G, Kutzler MA, Izmirly AM, Haddad EK. Alturki SO, et al. Among authors: kutzler ma. Front Immunol. 2020 Aug 19;11:1880. doi: 10.3389/fimmu.2020.01880. eCollection 2020. Front Immunol. 2020. PMID: 32973779 Free PMC article. Review.
The impact of immuno-aging on SARS-CoV-2 vaccine development.
Connors J, Bell MR, Marcy J, Kutzler M, Haddad EK. Connors J, et al. Geroscience. 2021 Feb;43(1):31-51. doi: 10.1007/s11357-021-00323-3. Epub 2021 Feb 11. Geroscience. 2021. PMID: 33569701 Free PMC article. Review.
Pre-vaccination frequency of circulatory Tfh is associated with robust immune response to TV003 dengue vaccine.
Izmirly AM, Pelletier AN, Connors J, Taramangalam B, Alturki SO, Gordon EA, Alturki SO, Mell JC, Swaminathan G, Karthik V, Kutzler MA, Kallas EG, Sekaly RP, Haddad EK. Izmirly AM, et al. Among authors: kutzler ma. PLoS Pathog. 2022 Jan 21;18(1):e1009903. doi: 10.1371/journal.ppat.1009903. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35061851 Free PMC article. Clinical Trial.
[No title available]
[No authors listed] [No authors listed] PMID: 35554532
Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1.
Cusimano GM, Gary EN, Bell MR, Warner BM, Connors J, Tursi NJ, Ali AR, Zhang S, Canziani G, Taramangalam B, Gordon EA, Chaiken IM, Wootton SK, Smith T, Ramos S, Kobasa D, Weiner DB, Kutzler MA, Haddad EK. Cusimano GM, et al. Among authors: kutzler ma. J Immunol. 2022 Jul 1;209(1):118-127. doi: 10.4049/jimmunol.2200056. Epub 2022 Jun 24. J Immunol. 2022. PMID: 35750334 Free PMC article.
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.
Gary EN, Tursi NJ, Warner BM, Cuismano G, Connors J, Parzych EM, Griffin BD, Bell MR, Ali AR, Frase D, Hojecki CE, Canziani GA, Chaiken I, Kannan T, Moffat E, Embury-Hyatt C, Wooton SK, Kossenkov A, Patel A, Kobasa D, Kutzler MA, Haddad EK, Weiner DB. Gary EN, et al. Among authors: kutzler ma. Front Immunol. 2023 Mar 14;14:1138609. doi: 10.3389/fimmu.2023.1138609. eCollection 2023. Front Immunol. 2023. PMID: 36999023 Free PMC article.
114 results