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SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery.
Frere JJ, Serafini RA, Pryce KD, Zazhytska M, Oishi K, Golynker I, Panis M, Zimering J, Horiuchi S, Hoagland DA, Møller R, Ruiz A, Kodra A, Overdevest JB, Canoll PD, Borczuk AC, Chandar V, Bram Y, Schwartz R, Lomvardas S, Zachariou V, tenOever BR. Frere JJ, et al. Among authors: tenoever br. Sci Transl Med. 2022 Sep 28;14(664):eabq3059. doi: 10.1126/scitranslmed.abq3059. Epub 2022 Sep 28. Sci Transl Med. 2022. PMID: 35857629 Free PMC article.
An in vivo RNAi screening approach to identify host determinants of virus replication.
Varble A, Benitez AA, Schmid S, Sachs D, Shim JV, Rodriguez-Barrueco R, Panis M, Crumiller M, Silva JM, Sachidanandam R, tenOever BR. Varble A, et al. Among authors: tenoever br. Cell Host Microbe. 2013 Sep 11;14(3):346-56. doi: 10.1016/j.chom.2013.08.007. Cell Host Microbe. 2013. PMID: 24034620 Free article.
Homologous recombination is an intrinsic defense against antiviral RNA interference.
Aguado LC, Jordan TX, Hsieh E, Blanco-Melo D, Heard J, Panis M, Vignuzzi M, tenOever BR. Aguado LC, et al. Among authors: tenoever br. Proc Natl Acad Sci U S A. 2018 Sep 25;115(39):E9211-E9219. doi: 10.1073/pnas.1810229115. Epub 2018 Sep 12. Proc Natl Acad Sci U S A. 2018. PMID: 30209219 Free PMC article.
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Blanco-Melo D, Nilsson-Payant BE, Liu WC, Uhl S, Hoagland D, Møller R, Jordan TX, Oishi K, Panis M, Sachs D, Wang TT, Schwartz RE, Lim JK, Albrecht RA, tenOever BR. Blanco-Melo D, et al. Among authors: tenoever br. Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15. Cell. 2020. PMID: 32416070 Free PMC article.
A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. Yang L, et al. Among authors: tenoever br. Cell Stem Cell. 2020 Jul 2;27(1):125-136.e7. doi: 10.1016/j.stem.2020.06.015. Epub 2020 Jun 19. Cell Stem Cell. 2020. PMID: 32579880 Free PMC article.
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: tenoever br. bioRxiv [Preprint]. 2020 Sep 21:2020.09.20.300574. doi: 10.1101/2020.09.20.300574. bioRxiv. 2020. PMID: 32995783 Free PMC article. Updated. Preprint.
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids.
Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, Tang X, Yaron TM, Zhang T, Uhl S, Bram Y, Richardson C, Zhu J, Zhao Z, Redmond D, Houghton S, Nguyen DT, Xu D, Wang X, Jessurun J, Borczuk A, Huang Y, Johnson JL, Liu Y, Xiang J, Wang H, Cantley LC, tenOever BR, Ho DD, Pan FC, Evans T, Chen HJ, Schwartz RE, Chen S. Han Y, et al. Among authors: tenoever br. Nature. 2021 Jan;589(7841):270-275. doi: 10.1038/s41586-020-2901-9. Epub 2020 Oct 28. Nature. 2021. PMID: 33116299 Free PMC article.
142 results