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SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice.
Dinnon KH 3rd, Leist SR, Okuda K, Dang H, Fritch EJ, Gully KL, De la Cruz G, Evangelista MD, Asakura T, Gilmore RC, Hawkins P, Nakano S, West A, Schäfer A, Gralinski LE, Everman JL, Sajuthi SP, Zweigart MR, Dong S, McBride J, Cooley MR, Hines JB, Love MK, Groshong SD, VanSchoiack A, Phelan SJ, Liang Y, Hether T, Leon M, Zumwalt RE, Barton LM, Duval EJ, Mukhopadhyay S, Stroberg E, Borczuk A, Thorne LB, Sakthivel MK, Lee YZ, Hagood JS, Mock JR, Seibold MA, O'Neal WK, Montgomery SA, Boucher RC, Baric RS. Dinnon KH 3rd, et al. Among authors: thorne lb. Sci Transl Med. 2022 Sep 28;14(664):eabo5070. doi: 10.1126/scitranslmed.abo5070. Epub 2022 Sep 28. Sci Transl Med. 2022. PMID: 35857635 Free PMC article.
Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications.
McElvaney OF, Asakura T, Meinig SL, Torres-Castillo JL, Hagan RS, Gabillard-Lefort C, Murphy MP, Thorne LB, Borczuk A, Reeves EP, Zumwalt RE, Mikami Y, Carroll TP, Okuda K, Hogan G, McElvaney OJ, Clarke J, McEvoy NL, Mallon PW, McCarthy C, Curley G, Wolfgang MC, Boucher RC, McElvaney NG. McElvaney OF, et al. Among authors: thorne lb. EBioMedicine. 2022 Mar;77:103894. doi: 10.1016/j.ebiom.2022.103894. Epub 2022 Feb 22. EBioMedicine. 2022. PMID: 35217407 Free PMC article.
Prevalence and Mechanisms of Mucus Accumulation in COVID-19 Lung Disease.
Kato T, Asakura T, Edwards CE, Dang H, Mikami Y, Okuda K, Chen G, Sun L, Gilmore RC, Hawkins P, De la Cruz G, Cooley MR, Bailey AB, Hewitt SM, Chertow DS, Borczuk AC, Salvatore S, Martinez FJ, Thorne LB, Askin FB, Ehre C, Randell SH, O'Neal WK, Baric RS, Boucher RC. Kato T, et al. Among authors: thorne lb. Am J Respir Crit Care Med. 2022 Dec 1;206(11):1336-1352. doi: 10.1164/rccm.202111-2606OC. Am J Respir Crit Care Med. 2022. PMID: 35816430 Free PMC article.
Validation of interobserver agreement in lung cancer assessment: hematoxylin-eosin diagnostic reproducibility for non-small cell lung cancer: the 2004 World Health Organization classification and therapeutically relevant subsets.
Grilley-Olson JE, Hayes DN, Moore DT, Leslie KO, Wilkerson MD, Qaqish BF, Hayward MC, Cabanski CR, Yin X, Socinski MA, Stinchcombe TE, Thorne LB, Allen TC, Banks PM, Beasley MB, Borczuk AC, Cagle PT, Christensen R, Colby TV, Deblois GG, Elmberger G, Graziano P, Hart CF, Jones KD, Maia DM, Miller CR, Nance KV, Travis WD, Funkhouser WK. Grilley-Olson JE, et al. Among authors: thorne lb. Arch Pathol Lab Med. 2013 Jan;137(1):32-40. doi: 10.5858/arpa.2012-0033-OA. Epub 2012 May 14. Arch Pathol Lab Med. 2013. PMID: 22583114 Free PMC article.
Fatal Pediatric COVID-19 Case With Seizures and Fulminant Cerebral Edema.
Ninan S, Thompson P, Gershon T, Ford N, Mills W, Jewells V, Thorne L, Saunders K, Bouldin T, Smedberg JR, Miller MB, Wu E, Tilly A, Sites J, Lercher D, Clement K, Walker T, Shea P, Joyner B, Smith R. Ninan S, et al. Child Neurol Open. 2021 Jun 14;8:2329048X211022532. doi: 10.1177/2329048X211022532. eCollection 2021 Jan-Dec. Child Neurol Open. 2021. PMID: 34179214 Free PMC article.
Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.
Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RR, Mullins M, Yin X, Miller CR, Thorne LB, Geiersbach KB, Muldrew KL, Funkhouser WK, Fan C, Hayward MC, Bayer S, Perou CM, Bernard PS. Wilkerson MD, et al. Among authors: thorne lb. J Mol Diagn. 2013 Jul;15(4):485-97. doi: 10.1016/j.jmoldx.2013.03.007. Epub 2013 May 20. J Mol Diagn. 2013. PMID: 23701907 Free PMC article.
Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types.
Wilkerson MD, Yin X, Hoadley KA, Liu Y, Hayward MC, Cabanski CR, Muldrew K, Miller CR, Randell SH, Socinski MA, Parsons AM, Funkhouser WK, Lee CB, Roberts PJ, Thorne L, Bernard PS, Perou CM, Hayes DN. Wilkerson MD, et al. Clin Cancer Res. 2010 Oct 1;16(19):4864-75. doi: 10.1158/1078-0432.CCR-10-0199. Epub 2010 Jul 19. Clin Cancer Res. 2010. PMID: 20643781 Free PMC article.
Differential pathogenesis of lung adenocarcinoma subtypes involving sequence mutations, copy number, chromosomal instability, and methylation.
Wilkerson MD, Yin X, Walter V, Zhao N, Cabanski CR, Hayward MC, Miller CR, Socinski MA, Parsons AM, Thorne LB, Haithcock BE, Veeramachaneni NK, Funkhouser WK, Randell SH, Bernard PS, Perou CM, Hayes DN. Wilkerson MD, et al. Among authors: thorne lb. PLoS One. 2012;7(5):e36530. doi: 10.1371/journal.pone.0036530. Epub 2012 May 10. PLoS One. 2012. PMID: 22590557 Free PMC article.
Molecular subtypes in head and neck cancer exhibit distinct patterns of chromosomal gain and loss of canonical cancer genes.
Walter V, Yin X, Wilkerson MD, Cabanski CR, Zhao N, Du Y, Ang MK, Hayward MC, Salazar AH, Hoadley KA, Fritchie K, Sailey CJ, Weissler MC, Shockley WW, Zanation AM, Hackman T, Thorne LB, Funkhouser WD, Muldrew KL, Olshan AF, Randell SH, Wright FA, Shores CG, Hayes DN. Walter V, et al. Among authors: thorne lb. PLoS One. 2013;8(2):e56823. doi: 10.1371/journal.pone.0056823. Epub 2013 Feb 22. PLoS One. 2013. PMID: 23451093 Free PMC article.
112 results