Dane A - Search Results

1

Phase 1-2 Trial of AAVS3 Gene Therapy in Patients with Hemophilia B.

Chowdary P, Shapiro S, Makris M, Evans G, Boyce S, Talks K, Dolan G, Reiss U, Phillips M, Riddell A, Peralta MR, Quaye M, Patch DW, Tuddenham E, Dane A, Watissée M, Long A, Nathwani A. Chowdary P, et al. Among authors: dane a. N Engl J Med. 2022 Jul 21;387(3):237-247. doi: 10.1056/NEJMoa2119913. N Engl J Med. 2022. PMID: 35857660 Free article. Clinical Trial.

2

Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.

Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Among authors: dane ap. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.

3

Potential limits of AAV-based gene therapy with the use of new transgenes expressing factor IX fusion proteins.

Le Quellec S, Dane A, Enjolras N, McIntosh J, Rosales C, Negrier C, Nathwani A. Le Quellec S, et al. Among authors: dane a. Haemophilia. 2019 Jan;25(1):e11-e18. doi: 10.1111/hae.13651. Epub 2018 Dec 6. Haemophilia. 2019. PMID: 30520547

4

Recombinant Adeno-Associated Viral Vectors Expressing Human Coagulation FIX-E456H Variant in Hemophilia B Mice.

Le Quellec S, Dane AP, Barbon E, Bordet JC, Mingozzi F, Dargaud Y, Marais T, Biferi MG, Négrier C, Nathawani AC, Enjolras N. Le Quellec S, et al. Thromb Haemost. 2019 Dec;119(12):1956-1967. doi: 10.1055/s-0039-1697658. Epub 2019 Oct 28. Thromb Haemost. 2019. PMID: 31659733

5

Gene delivery to the juvenile mouse liver using AAV2/8 vectors.

Cunningham SC, Dane AP, Spinoulas A, Logan GJ, Alexander IE. Cunningham SC, et al. Among authors: dane ap. Mol Ther. 2008 Jun;16(6):1081-8. doi: 10.1038/mt.2008.72. Epub 2008 Apr 15. Mol Ther. 2008. PMID: 18414478 Free article.

6

Sexually dimorphic patterns of episomal rAAV genome persistence in the adult mouse liver and correlation with hepatocellular proliferation.

Dane AP, Cunningham SC, Graf NS, Alexander IE. Dane AP, et al. Mol Ther. 2009 Sep;17(9):1548-54. doi: 10.1038/mt.2009.139. Epub 2009 Jun 30. Mol Ther. 2009. PMID: 19568224 Free PMC article.

7

Selection and evaluation of clinically relevant AAV variants in a xenograft liver model.

Lisowski L, Dane AP, Chu K, Zhang Y, Cunningham SC, Wilson EM, Nygaard S, Grompe M, Alexander IE, Kay MA. Lisowski L, et al. Among authors: dane ap. Nature. 2014 Feb 20;506(7488):382-6. doi: 10.1038/nature12875. Epub 2013 Dec 25. Nature. 2014. PMID: 24390344 Free PMC article.

8

Comparison of gene transfer to the murine liver following intraperitoneal and intraportal delivery of hepatotropic AAV pseudo-serotypes.

Dane AP, Wowro SJ, Cunningham SC, Alexander IE. Dane AP, et al. Gene Ther. 2013 Apr;20(4):460-4. doi: 10.1038/gt.2012.67. Epub 2012 Aug 16. Gene Ther. 2013. PMID: 22895507

9

Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus.

Dane AP, Cunningham SC, Kok CY, Logan GJ, Alexander IE. Dane AP, et al. Gene Ther. 2015 Nov;22(11):917-22. doi: 10.1038/gt.2015.66. Epub 2015 Jul 30. Gene Ther. 2015. PMID: 26224361

10

Induction and prevention of severe hyperammonemia in the spfash mouse model of ornithine transcarbamylase deficiency using shRNA and rAAV-mediated gene delivery.

Cunningham SC, Kok CY, Dane AP, Carpenter K, Kizana E, Kuchel PW, Alexander IE. Cunningham SC, et al. Mol Ther. 2011 May;19(5):854-9. doi: 10.1038/mt.2011.32. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386824 Free PMC article.

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