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Proprotein convertase subtilisin/kexin type 9 is a psoriasis-susceptibility locus that is negatively related to IL36G.
Merleev A, Ji-Xu A, Toussi A, Tsoi LC, Le ST, Luxardi G, Xing X, Wasikowski R, Liakos W, Brüggen MC, Elder JT, Adamopoulos IE, Izumiya Y, Leal AR, Li Q, Kuzminykh NY, Kirane A, Marusina AI, Gudjonsson JE, Maverakis E. Merleev A, et al. Among authors: izumiya y. JCI Insight. 2022 Aug 22;7(16):e141193. doi: 10.1172/jci.insight.141193. JCI Insight. 2022. PMID: 35862195 Free PMC article.
Biogeographic and disease-specific alterations in epidermal lipid composition and single-cell analysis of acral keratinocytes.
Merleev AA, Le ST, Alexanian C, Toussi A, Xie Y, Marusina AI, Watkins SM, Patel F, Billi AC, Wiedemann J, Izumiya Y, Kumar A, Uppala R, Kahlenberg JM, Liu FT, Adamopoulos IE, Wang EA, Ma C, Cheng MY, Xiong H, Kirane A, Luxardi G, Andersen B, Tsoi LC, Lebrilla CB, Gudjonsson JE, Maverakis E. Merleev AA, et al. Among authors: izumiya y. JCI Insight. 2022 Aug 22;7(16):e159762. doi: 10.1172/jci.insight.159762. JCI Insight. 2022. PMID: 35900871 Free PMC article.
KSHV uses viral IL6 to expand infected immunosuppressive macrophages.
Shimoda M, Inagaki T, Davis RR, Merleev A, Tepper CG, Maverakis E, Izumiya Y. Shimoda M, et al. Among authors: izumiya y. bioRxiv [Preprint]. 2023 Mar 26:2023.03.05.531224. doi: 10.1101/2023.03.05.531224. bioRxiv. 2023. PMID: 36945595 Free PMC article. Preprint.
Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma.
Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y. Zhou F, et al. Among authors: izumiya y. Mol Cancer Ther. 2017 Nov;16(11):2627-2638. doi: 10.1158/1535-7163.MCT-17-0041. Epub 2017 Aug 28. Mol Cancer Ther. 2017. PMID: 28847988 Free PMC article.
KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.
Kumar A, Lyu Y, Yanagihashi Y, Chantarasrivong C, Majerciak V, Salemi M, Wang KH, Inagaki T, Chuang F, Davis RR, Tepper CG, Nakano K, Izumiya C, Shimoda M, Nakajima KI, Merleev A, Zheng ZM, Campbell M, Izumiya Y. Kumar A, et al. Among authors: izumiya c, izumiya y. Cell Rep. 2022 May 10;39(6):110788. doi: 10.1016/j.celrep.2022.110788. Cell Rep. 2022. PMID: 35545047 Free PMC article.
Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification.
Izumiya Y, Ellison TJ, Yeh ET, Jung JU, Luciw PA, Kung HJ. Izumiya Y, et al. J Virol. 2005 Aug;79(15):9912-25. doi: 10.1128/JVI.79.15.9912-9925.2005. J Virol. 2005. PMID: 16014952 Free PMC article.
Previously, we demonstrated that the early lytic gene product K-bZIP is a transcriptional repressor that affects a subset of viral gene transcriptions mediated by the viral transactivator K-Rta (Y. Izumiya et al. J. Virol. 77:1441-1451, 2003). Sumoylation has emerge …
Previously, we demonstrated that the early lytic gene product K-bZIP is a transcriptional repressor that affects a subset of viral gene tran …
316 results