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The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence.
Strongin Z, Hoang TN, Tharp GK, Rahmberg AR, Harper JL, Nguyen K, Franchitti L, Cervasi B, Lee M, Zhang Z, Boritz EA, Silvestri G, Marconi VC, Bosinger SE, Brenchley JM, Kulpa DA, Paiardini M. Strongin Z, et al. Among authors: kulpa da. PLoS Pathog. 2022 Jul 22;18(7):e1010723. doi: 10.1371/journal.ppat.1010723. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35867722 Free PMC article.
Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
Gavegnano C, Brehm JH, Dupuy FP, Talla A, Ribeiro SP, Kulpa DA, Cameron C, Santos S, Hurwitz SJ, Marconi VC, Routy JP, Sabbagh L, Schinazi RF, Sékaly RP. Gavegnano C, et al. Among authors: kulpa da. PLoS Pathog. 2017 Dec 21;13(12):e1006740. doi: 10.1371/journal.ppat.1006740. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29267399 Free PMC article.
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.
Wonderlich ER, Subramanian K, Cox B, Wiegand A, Lackman-Smith C, Bale MJ, Stone M, Hoh R, Kearney MF, Maldarelli F, Deeks SG, Busch MP, Ptak RG, Kulpa DA. Wonderlich ER, et al. Among authors: kulpa da. PLoS Pathog. 2019 Oct 14;15(10):e1008074. doi: 10.1371/journal.ppat.1008074. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31609991 Free PMC article.
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: kulpa da. Nature. 2020 Feb;578(7793):154-159. doi: 10.1038/s41586-020-1946-0. Epub 2020 Jan 22. Nature. 2020. PMID: 31969705 Free PMC article.
Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: kulpa da. Nature. 2020 Feb;578(7796):E21. doi: 10.1038/s41586-020-2002-9. Nature. 2020. PMID: 32015546
CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
Mavigner M, Liao LE, Brooks AD, Ke R, Mattingly C, Schoof N, McBrien J, Carnathan D, Liang S, Vanderford TH, Paiardini M, Kulpa D, Lifson JD, Dunham RM, Easley KA, Margolis DM, Perelson AS, Silvestri G, Chahroudi A. Mavigner M, et al. J Virol. 2021 Mar 25;95(8):e01429-20. doi: 10.1128/JVI.01429-20. Epub 2021 Feb 10. J Virol. 2021. PMID: 33568515 Free PMC article.
40 results