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GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level.
Schröder J, Chegwidden L, Maj C, Gehlen J, Speller J, Böhmer AC, Borisov O, Hess T, Kreuser N, Venerito M, Alakus H, May A, Gerges C, Schmidt T, Thieme R, Heider D, Hillmer AM, Reingruber J, Lyros O, Dietrich A, Hoffmeister A, Mehdorn M, Lordick F, Stocker G, Hohaus M, Reim D, Kandler J, Müller M, Ebigbo A, Fuchs C, Bruns CJ, Hölscher AH, Lang H, Grimminger PP, Dakkak D, Vashist Y, May S, Görg S, Franke A, Ellinghaus D, Galavotti S, Veits L, Weismüller J, Dommermuth J, Benner U, Rösch T, Messmann H, Schumacher B, Neuhaus H, Schmidt C, Wissinowski TT, Nöthen MM; Wellcome Trust Case Control Consortium 2 (WTCCC2); Esophageal Adenocarcinoma Genetics Consortium (EAGLE); Barrett's and Esophageal Adenocarcinoma Consortium (BEACON); Dong J, Ong JS, Buas MF, Thrift AP, Vaughan TL, Tomlinson I, Whiteman DC, Fitzgerald RC, Jankowski J, Vieth M, Mayr A, Gharahkhani P, MacGregor S, Gockel I, Palles C, Schumacher J. Schröder J, et al. Among authors: whiteman dc. Gut. 2023 Apr;72(4):612-623. doi: 10.1136/gutjnl-2021-326698. Epub 2022 Jul 26. Gut. 2023. PMID: 35882562
Leptin and the risk of Barrett's oesophagus.
Kendall BJ, Macdonald GA, Hayward NK, Prins JB, Brown I, Walker N, Pandeya N, Green AC, Webb PM, Whiteman DC; Study of Digestive Health. Kendall BJ, et al. Among authors: whiteman dc. Gut. 2008 Apr;57(4):448-54. doi: 10.1136/gut.2007.131243. Epub 2008 Jan 4. Gut. 2008. PMID: 18178609
Reproductive and sex hormonal factors and oesophageal and gastric junction adenocarcinoma: a pooled analysis.
Cronin-Fenton DP, Murray LJ, Whiteman DC, Cardwell C, Webb PM, Jordan SJ, Corley DA, Sharp L, Lagergren J; Barrett's Esophagus, Adenocarcinoma Consortium (BEACON) Investigators. Cronin-Fenton DP, et al. Among authors: whiteman dc. Eur J Cancer. 2010 Jul;46(11):2067-76. doi: 10.1016/j.ejca.2010.03.032. Epub 2010 Apr 22. Eur J Cancer. 2010. PMID: 20456945 Free PMC article.
Cigarette smoking and adenocarcinomas of the esophagus and esophagogastric junction: a pooled analysis from the international BEACON consortium.
Cook MB, Kamangar F, Whiteman DC, Freedman ND, Gammon MD, Bernstein L, Brown LM, Risch HA, Ye W, Sharp L, Pandeya N, Webb PM, Wu AH, Ward MH, Giffen C, Casson AG, Abnet CC, Murray LJ, Corley DA, Nyrén O, Vaughan TL, Chow WH. Cook MB, et al. Among authors: whiteman dc. J Natl Cancer Inst. 2010 Sep 8;102(17):1344-53. doi: 10.1093/jnci/djq289. Epub 2010 Aug 17. J Natl Cancer Inst. 2010. PMID: 20716718 Free PMC article.
Alcohol intake and risk of oesophageal adenocarcinoma: a pooled analysis from the BEACON Consortium.
Freedman ND, Murray LJ, Kamangar F, Abnet CC, Cook MB, Nyrén O, Ye W, Wu AH, Bernstein L, Brown LM, Ward MH, Pandeya N, Green AC, Casson AG, Giffen C, Risch HA, Gammon MD, Chow WH, Vaughan TL, Corley DA, Whiteman DC. Freedman ND, et al. Among authors: whiteman dc. Gut. 2011 Aug;60(8):1029-37. doi: 10.1136/gut.2010.233866. Epub 2011 Mar 14. Gut. 2011. PMID: 21406386 Free PMC article.
Lifetime alcohol consumption and risk of Barrett's Esophagus.
Thrift AP, Pandeya N, Smith KJ, Mallitt KA, Green AC, Webb PM, Whiteman DC. Thrift AP, et al. Among authors: whiteman dc. Am J Gastroenterol. 2011 Jul;106(7):1220-30. doi: 10.1038/ajg.2011.89. Epub 2011 Mar 22. Am J Gastroenterol. 2011. PMID: 21427711
559 results