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290 results

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Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.
Han H, Best AJ, Braunschweig U, Mikolajewicz N, Li JD, Roth J, Chowdhury F, Mantica F, Nabeel-Shah S, Parada G, Brown KR, O'Hanlon D, Wei J, Yao Y, Zid AA, Comsa LC, Jen M, Wang J, Datti A, Gonatopoulos-Pournatzis T, Weatheritt RJ, Greenblatt JF, Wrana JL, Irimia M, Gingras AC, Moffat J, Blencowe BJ. Han H, et al. Among authors: wrana jl. Mol Cell. 2022 Aug 18;82(16):2982-2999.e14. doi: 10.1016/j.molcel.2022.06.036. Epub 2022 Jul 31. Mol Cell. 2022. PMID: 35914530 Free PMC article.
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens.
Smith KM, Datti A, Fujitani M, Grinshtein N, Zhang L, Morozova O, Blakely KM, Rotenberg SA, Hansford LM, Miller FD, Yeger H, Irwin MS, Moffat J, Marra MA, Baruchel S, Wrana JL, Kaplan DR. Smith KM, et al. Among authors: wrana jl. EMBO Mol Med. 2010 Sep;2(9):371-84. doi: 10.1002/emmm.201000093. EMBO Mol Med. 2010. PMID: 20721990 Free PMC article.
Inhibition of SREBP1 sensitizes cells to death ligands.
Eberhard Y, Gronda M, Hurren R, Datti A, MacLean N, Ketela T, Moffat J, Wrana JL, Schimmer AD. Eberhard Y, et al. Among authors: wrana jl. Oncotarget. 2011 Mar;2(3):186-96. doi: 10.18632/oncotarget.239. Oncotarget. 2011. PMID: 21406729 Free PMC article.
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, Nagy A, Wrana JL, Blencowe BJ. Gabut M, et al. Among authors: wrana jl. Cell. 2011 Sep 30;147(1):132-46. doi: 10.1016/j.cell.2011.08.023. Epub 2011 Sep 15. Cell. 2011. PMID: 21924763 Free article.
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD. Skrtić M, et al. Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015. Cancer Cell. 2011. PMID: 22094260 Free PMC article.
Essential gene profiles in breast, pancreatic, and ovarian cancer cells.
Marcotte R, Brown KR, Suarez F, Sayad A, Karamboulas K, Krzyzanowski PM, Sircoulomb F, Medrano M, Fedyshyn Y, Koh JLY, van Dyk D, Fedyshyn B, Luhova M, Brito GC, Vizeacoumar FJ, Vizeacoumar FS, Datti A, Kasimer D, Buzina A, Mero P, Misquitta C, Normand J, Haider M, Ketela T, Wrana JL, Rottapel R, Neel BG, Moffat J. Marcotte R, et al. Among authors: wrana jl. Cancer Discov. 2012 Feb;2(2):172-189. doi: 10.1158/2159-8290.CD-11-0224. Epub 2011 Dec 29. Cancer Discov. 2012. PMID: 22585861 Free PMC article.
290 results