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Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
Chen CW, Guan BJ, Alzahrani MR, Gao Z, Gao L, Bracey S, Wu J, Mbow CA, Jobava R, Haataja L, Zalavadia AH, Schaffer AE, Lee H, LaFramboise T, Bederman I, Arvan P, Mathews CE, Gerling IC, Kaestner KH, Tirosh B, Engin F, Hatzoglou M. Chen CW, et al. Among authors: kaestner kh. Nat Commun. 2022 Aug 8;13(1):4621. doi: 10.1038/s41467-022-32425-7. Nat Commun. 2022. PMID: 35941159 Free PMC article.
Epigenomic plasticity enables human pancreatic α to β cell reprogramming.
Bramswig NC, Everett LJ, Schug J, Dorrell C, Liu C, Luo Y, Streeter PR, Naji A, Grompe M, Kaestner KH. Bramswig NC, et al. Among authors: kaestner kh. J Clin Invest. 2013 Mar;123(3):1275-84. doi: 10.1172/JCI66514. Epub 2013 Feb 22. J Clin Invest. 2013. PMID: 23434589 Free PMC article.
Islet-1 Is essential for pancreatic β-cell function.
Ediger BN, Du A, Liu J, Hunter CS, Walp ER, Schug J, Kaestner KH, Stein R, Stoffers DA, May CL. Ediger BN, et al. Among authors: kaestner kh. Diabetes. 2014 Dec;63(12):4206-17. doi: 10.2337/db14-0096. Epub 2014 Jul 15. Diabetes. 2014. PMID: 25028525 Free PMC article.
Human islets contain four distinct subtypes of β cells.
Dorrell C, Schug J, Canaday PS, Russ HA, Tarlow BD, Grompe MT, Horton T, Hebrok M, Streeter PR, Kaestner KH, Grompe M. Dorrell C, et al. Among authors: kaestner kh. Nat Commun. 2016 Jul 11;7:11756. doi: 10.1038/ncomms11756. Nat Commun. 2016. PMID: 27399229 Free PMC article.
Effects of ageing and senescence on pancreatic β-cell function.
Helman A, Avrahami D, Klochendler A, Glaser B, Kaestner KH, Ben-Porath I, Dor Y. Helman A, et al. Among authors: kaestner kh. Diabetes Obes Metab. 2016 Sep;18 Suppl 1:58-62. doi: 10.1111/dom.12719. Diabetes Obes Metab. 2016. PMID: 27615132 Review.
413 results