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Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health.
Gadd DA, Hillary RF, McCartney DL, Shi L, Stolicyn A, Robertson NA, Walker RM, McGeachan RI, Campbell A, Xueyi S, Barbu MC, Green C, Morris SW, Harris MA, Backhouse EV, Wardlaw JM, Steele JD, Oyarzún DA, Muniz-Terrera G, Ritchie C, Nevado-Holgado A, Chandra T, Hayward C, Evans KL, Porteous DJ, Cox SR, Whalley HC, McIntosh AM, Marioni RE. Gadd DA, et al. Among authors: chandra t. Nat Commun. 2022 Aug 9;13(1):4670. doi: 10.1038/s41467-022-32319-8. Nat Commun. 2022. PMID: 35945220 Free PMC article.
Age-related clonal haemopoiesis is associated with increased epigenetic age.
Robertson NA, Hillary RF, McCartney DL, Terradas-Terradas M, Higham J, Sproul D, Deary IJ, Kirschner K, Marioni RE, Chandra T. Robertson NA, et al. Among authors: chandra t. Curr Biol. 2019 Aug 19;29(16):R786-R787. doi: 10.1016/j.cub.2019.07.011. Curr Biol. 2019. PMID: 31430471 Free article.
An epigenome-wide association study of sex-specific chronological ageing.
McCartney DL, Zhang F, Hillary RF, Zhang Q, Stevenson AJ, Walker RM, Bermingham ML, Boutin T, Morris SW, Campbell A, Murray AD, Whalley HC, Porteous DJ, Hayward C, Evans KL, Chandra T, Deary IJ, McIntosh AM, Yang J, Visscher PM, McRae AF, Marioni RE. McCartney DL, et al. Among authors: chandra t. Genome Med. 2019 Dec 31;12(1):1. doi: 10.1186/s13073-019-0693-z. Genome Med. 2019. PMID: 31892350 Free PMC article.
Purifying stem cell-derived red blood cells: a high-throughput label-free downstream processing strategy based on microfluidic spiral inertial separation and membrane filtration.
Guzniczak E, Otto O, Whyte G, Chandra T, Robertson NA, Willoughby N, Jimenez M, Bridle H. Guzniczak E, et al. Among authors: chandra t. Biotechnol Bioeng. 2020 Jul;117(7):2032-2045. doi: 10.1002/bit.27319. Epub 2020 Mar 15. Biotechnol Bioeng. 2020. PMID: 32100873 Free PMC article.
Clonality in haematopoietic stem cell ageing.
Terradas-Terradas M, Robertson NA, Chandra T, Kirschner K. Terradas-Terradas M, et al. Among authors: chandra t. Mech Ageing Dev. 2020 Jul;189:111279. doi: 10.1016/j.mad.2020.111279. Epub 2020 Jun 8. Mech Ageing Dev. 2020. PMID: 32526214 Free PMC article. Review.
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects.
Robertson NA, Latorre-Crespo E, Terradas-Terradas M, Lemos-Portela J, Purcell AC, Livesey BJ, Hillary RF, Murphy L, Fawkes A, MacGillivray L, Copland M, Marioni RE, Marsh JA, Harris SE, Cox SR, Deary IJ, Schumacher LJ, Kirschner K, Chandra T. Robertson NA, et al. Among authors: chandra t. Nat Med. 2022 Jul;28(7):1439-1446. doi: 10.1038/s41591-022-01883-3. Epub 2022 Jul 4. Nat Med. 2022. PMID: 35788175 Free PMC article.
cGAS surveillance of micronuclei links genome instability to innate immunity.
Mackenzie KJ, Carroll P, Martin CA, Murina O, Fluteau A, Simpson DJ, Olova N, Sutcliffe H, Rainger JK, Leitch A, Osborn RT, Wheeler AP, Nowotny M, Gilbert N, Chandra T, Reijns MAM, Jackson AP. Mackenzie KJ, et al. Among authors: chandra t. Nature. 2017 Aug 24;548(7668):461-465. doi: 10.1038/nature23449. Epub 2017 Jul 24. Nature. 2017. PMID: 28738408 Free PMC article.
Epigenetic age prediction.
Simpson DJ, Chandra T. Simpson DJ, et al. Among authors: chandra t. Aging Cell. 2021 Sep;20(9):e13452. doi: 10.1111/acel.13452. Epub 2021 Aug 20. Aging Cell. 2021. PMID: 34415665 Free PMC article. Review.
331 results