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Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV 2nd, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL. Muratore CR, et al. Among authors: pearse rv 2nd. Stem Cell Reports. 2017 Dec 12;9(6):1868-1884. doi: 10.1016/j.stemcr.2017.10.015. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153990 Free PMC article.
Somatic mosaicism of sex chromosomes in the blood and brain.
Graham EJ, Vermeulen M, Vardarajan B, Bennett D, De Jager P, Pearse RV 2nd, Young-Pearse TL, Mostafavi S. Graham EJ, et al. Among authors: pearse rv 2nd. Brain Res. 2019 Oct 15;1721:146345. doi: 10.1016/j.brainres.2019.146345. Epub 2019 Jul 23. Brain Res. 2019. PMID: 31348909 Free PMC article.
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, Young-Pearse TL. Lagomarsino VN, et al. Among authors: pearse rv 2nd. Neuron. 2021 Nov 3;109(21):3402-3420.e9. doi: 10.1016/j.neuron.2021.08.003. Epub 2021 Sep 1. Neuron. 2021. PMID: 34473944 Free PMC article.
APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons.
Wu CI, Vinton EA, Pearse RV 2nd, Heo K, Aylward AJ, Hsieh YC, Bi Y, Adeleye S, Fancher S, Duong DM, Seyfried NT, Schwarz TL, Young-Pearse TL. Wu CI, et al. Among authors: pearse rv 2nd. Mol Psychiatry. 2022 Apr;27(4):1970-1989. doi: 10.1038/s41380-022-01454-5. Epub 2022 Feb 23. Mol Psychiatry. 2022. PMID: 35194165 Free PMC article.
Mosaic loss of Chromosome Y in aged human microglia.
Vermeulen MC, Pearse R, Young-Pearse T, Mostafavi S. Vermeulen MC, et al. Genome Res. 2022 Oct;32(10):1795-1807. doi: 10.1101/gr.276409.121. Epub 2022 Aug 30. Genome Res. 2022. PMID: 36041859 Free PMC article.
33 results