Nickels ML - Search Results

1

Investigating Tau and Amyloid Tracer Skull Binding in Studies of Alzheimer Disease.

Flores S, Chen CD, Su Y, Dincer A, Keefe SJ, McKay NS, Paulick AM, Perez-Carrillo GG, Wang L, Hornbeck RC, Goyal M, Vlassenko A, Schwarz S, Nickels ML, Wong DF, Tu Z, McConathy JE, Morris JC, Benzinger TLS, Gordon BA. Flores S, et al. Among authors: nickels ml. J Nucl Med. 2023 Feb;64(2):287-293. doi: 10.2967/jnumed.122.263948. Epub 2022 Aug 11. J Nucl Med. 2023. PMID: 35953305 Free PMC article.

2

Phase 1 Evaluation of ¹¹C-CS1P1 to Assess Safety and Dosimetry in Human Participants.

Brier MR, Hamdi M, Rajamanikam J, Zhao H, Mansor S, Jones LA, Rahmani F, Jindal S, Koudelis D, Perlmutter JS, Wong DF, Nickels M, Ippolito JE, Gropler RJ, Schindler TH, Laforest R, Tu Z, Benzinger TLS. Brier MR, et al. J Nucl Med. 2022 Nov;63(11):1775-1782. doi: 10.2967/jnumed.121.263189. Epub 2022 Mar 24. J Nucl Med. 2022. PMID: 35332093 Free PMC article. Clinical Trial.

3

N-[¹⁸F]-Fluoroacetylcrizotinib: A potentially potent and selective PET tracer for molecular imaging of non-small cell lung cancer.

Buck JR, Saleh S, Claus T, Lovly C, Hight MR, Nickels ML, Noor Tantawy M, Charles Manning H. Buck JR, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127257. doi: 10.1016/j.bmcl.2020.127257. Epub 2020 Jun 2. Bioorg Med Chem Lett. 2020. PMID: 32631505 Free PMC article.

4

Quantitative preclinical imaging of TSPO expression in glioma using N,N-diethyl-2-(2-(4-(2-18F-fluoroethoxy)phenyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)acetamide.

Tang D, Hight MR, McKinley ET, Fu A, Buck JR, Smith RA, Tantawy MN, Peterson TE, Colvin DC, Ansari MS, Nickels M, Manning HC. Tang D, et al. J Nucl Med. 2012 Feb;53(2):287-94. doi: 10.2967/jnumed.111.095653. Epub 2012 Jan 17. J Nucl Med. 2012. PMID: 22251555 Free PMC article.

5

Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.

Tang D, McKinley ET, Hight MR, Uddin MI, Harp JM, Fu A, Nickels ML, Buck JR, Manning HC. Tang D, et al. Among authors: nickels ml. J Med Chem. 2013 Apr 25;56(8):3429-33. doi: 10.1021/jm4001874. Epub 2013 Apr 3. J Med Chem. 2013. PMID: 23521048 Free PMC article.

6

Facile synthesis of SSR180575 and discovery of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[(18)F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide, a potent pyridazinoindole ligand for PET imaging of TSPO in cancer.

Cheung YY, Nickels ML, Tang D, Buck JR, Manning HC. Cheung YY, et al. Among authors: nickels ml. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4466-4471. doi: 10.1016/j.bmcl.2014.07.091. Epub 2014 Aug 8. Bioorg Med Chem Lett. 2014. PMID: 25172419 Free PMC article.

7

Preclinical Evaluation of 4-[18F]Fluoroglutamine PET to Assess ASCT2 Expression in Lung Cancer.

Hassanein M, Hight MR, Buck JR, Tantawy MN, Nickels ML, Hoeksema MD, Harris BK, Boyd K, Massion PP, Manning HC. Hassanein M, et al. Among authors: nickels ml. Mol Imaging Biol. 2016 Feb;18(1):18-23. doi: 10.1007/s11307-015-0862-4. Mol Imaging Biol. 2016. PMID: 25971659 Free PMC article.

8

A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.

Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC. Hight MR, et al. Among authors: nickels ml. Clin Cancer Res. 2014 Apr 15;20(8):2126-35. doi: 10.1158/1078-0432.CCR-13-2444. Epub 2014 Feb 26. Clin Cancer Res. 2014. PMID: 24573549 Free PMC article.

9

High-yielding, automated production of 3'-deoxy-3'-[(18)F]fluorothymidine using a modified Bioscan Coincidence FDG reaction module.

Cheung YY, Nickels ML, McKinley ET, Buck JR, Manning HC. Cheung YY, et al. Among authors: nickels ml. Appl Radiat Isot. 2015 Mar;97:47-51. doi: 10.1016/j.apradiso.2014.11.011. Epub 2014 Dec 15. Appl Radiat Isot. 2015. PMID: 25531913 Free PMC article.

10

Evaluation of TSPO PET Ligands [¹⁸F]VUIIS1009A and [¹⁸F]VUIIS1009B: Tracers for Cancer Imaging.

Tang D, Li J, Buck JR, Tantawy MN, Xia Y, Harp JM, Nickels ML, Meiler J, Manning HC. Tang D, et al. Among authors: nickels ml. Mol Imaging Biol. 2017 Aug;19(4):578-588. doi: 10.1007/s11307-016-1027-9. Mol Imaging Biol. 2017. PMID: 27853987 Free PMC article.

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