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Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response.
Zhang P, Kitchen-Smith I, Xiong L, Stracquadanio G, Brown K, Richter PH, Wallace MD, Bond E, Sahgal N, Moore S, Nornes S, De Val S, Surakhy M, Sims D, Wang X, Bell DA, Zeron-Medina J, Jiang Y, Ryan AJ, Selfe JL, Shipley J, Kar S, Pharoah PD, Loveday C, Jansen R, Grochola LF, Palles C, Protheroe A, Millar V, Ebner DV, Pagadala M, Blagden SP, Maughan TS, Domingo E, Tomlinson I, Turnbull C, Carter H, Bond GL. Zhang P, et al. Among authors: carter h. Cancer Res. 2021 Apr 1;81(7):1667-1680. doi: 10.1158/0008-5472.CAN-20-0177. Epub 2021 Feb 8. Cancer Res. 2021. PMID: 33558336 Free PMC article.
Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response.
Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. Pagadala M, et al. Among authors: carter h. Nat Commun. 2023 May 12;14(1):2744. doi: 10.1038/s41467-023-38271-5. Nat Commun. 2023. PMID: 37173324 Free PMC article.
Network-based stratification of tumor mutations.
Hofree M, Shen JP, Carter H, Gross A, Ideker T. Hofree M, et al. Among authors: carter h. Nat Methods. 2013 Nov;10(11):1108-15. doi: 10.1038/nmeth.2651. Epub 2013 Sep 15. Nat Methods. 2013. PMID: 24037242 Free PMC article.
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.
Gross AM, Orosco RK, Shen JP, Egloff AM, Carter H, Hofree M, Choueiri M, Coffey CS, Lippman SM, Hayes DN, Cohen EE, Grandis JR, Nguyen QT, Ideker T. Gross AM, et al. Among authors: carter h. Nat Genet. 2014 Sep;46(9):939-43. doi: 10.1038/ng.3051. Epub 2014 Aug 3. Nat Genet. 2014. PMID: 25086664 Free PMC article.
Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma.
Xu RH, Wei W, Krawczyk M, Wang W, Luo H, Flagg K, Yi S, Shi W, Quan Q, Li K, Zheng L, Zhang H, Caughey BA, Zhao Q, Hou J, Zhang R, Xu Y, Cai H, Li G, Hou R, Zhong Z, Lin D, Fu X, Zhu J, Duan Y, Yu M, Ying B, Zhang W, Wang J, Zhang E, Zhang C, Li O, Guo R, Carter H, Zhu JK, Hao X, Zhang K. Xu RH, et al. Among authors: carter h. Nat Mater. 2017 Nov;16(11):1155-1161. doi: 10.1038/nmat4997. Epub 2017 Oct 9. Nat Mater. 2017. PMID: 29035356 Clinical Trial.
MHC-I genotype and tumor mutational burden predict response to immunotherapy.
Goodman AM, Castro A, Pyke RM, Okamura R, Kato S, Riviere P, Frampton G, Sokol E, Zhang X, Ball ED, Carter H, Kurzrock R. Goodman AM, et al. Among authors: carter h. Genome Med. 2020 May 19;12(1):45. doi: 10.1186/s13073-020-00743-4. Genome Med. 2020. PMID: 32430031 Free PMC article.
1,184 results