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Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D1 Dopamine Receptor Signaling and Behaviors.
Lin R, Learman LN, Na CH, Renuse S, Chen KT, Chen PY, Lee GH, Xiao B, Resnick SM, Troncoso JC, Szumlinski KK, Linden DJ, Park JM, Savonenko A, Pandey A, Worley PF. Lin R, et al. Among authors: worley pf. Biol Psychiatry. 2021 Jun 1;89(11):1058-1072. doi: 10.1016/j.biopsych.2020.10.012. Epub 2020 Oct 27. Biol Psychiatry. 2021. PMID: 33353667 Free PMC article.
CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders.
Kim NS, Ringeling FR, Zhou Y, Nguyen HN, Temme SJ, Lin YT, Eacker S, Dawson VL, Dawson TM, Xiao B, Hsu KS, Canzar S, Li W, Worley P, Christian KM, Yoon KJ, Song H, Ming GL. Kim NS, et al. Biol Psychiatry. 2022 Nov 15;92(10):815-826. doi: 10.1016/j.biopsych.2021.04.023. Epub 2021 May 5. Biol Psychiatry. 2022. PMID: 34247782 Free PMC article.
GATOR2 complex-mediated amino acid signaling regulates brain myelination.
Yu Z, Yang Z, Ren G, Wang Y, Luo X, Zhu F, Yu S, Jia L, Chen M, Worley PF, Xiao B. Yu Z, et al. Among authors: worley pf. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2110917119. doi: 10.1073/pnas.2110917119. Proc Natl Acad Sci U S A. 2022. PMID: 35022234 Free PMC article.
RHEB is a potential therapeutic target in T cell acute lymphoblastic leukemia.
Pham LT, Peng H, Ueno M, Kohno S, Kasada A, Hosomichi K, Sato T, Kurayoshi K, Kobayashi M, Tadokoro Y, Kasahara A, Shoulkamy MI, Xiao B, Worley PF, Takahashi C, Tajima A, Hirao A. Pham LT, et al. Among authors: worley pf. Biochem Biophys Res Commun. 2022 Sep 17;621:74-79. doi: 10.1016/j.bbrc.2022.06.089. Epub 2022 Jun 30. Biochem Biophys Res Commun. 2022. PMID: 35810594
306 results