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Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.
Reader JC, Matthews TP, Klair S, Cheung KM, Scanlon J, Proisy N, Addison G, Ellard J, Piton N, Taylor S, Cherry M, Fisher M, Boxall K, Burns S, Walton MI, Westwood IM, Hayes A, Eve P, Valenti M, de Haven Brandon A, Box G, van Montfort RL, Williams DH, Aherne GW, Raynaud FI, Eccles SA, Garrett MD, Collins I. Reader JC, et al. Among authors: scanlon j. J Med Chem. 2011 Dec 22;54(24):8328-42. doi: 10.1021/jm2007326. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22111927 Free PMC article.
Time of day does not impact spinal serotonin levels in humans.
Anand SK, Lavadi RS, Johnston BR, Chalif JI, Scanlon JM, Wang W, Agarwal N, Hamilton DK, Fields DP, Van't Land CW. Anand SK, et al. Among authors: scanlon jm. Synapse. 2024 May;78(3):e22291. doi: 10.1002/syn.22291. Synapse. 2024. PMID: 38733105
Draft of WHO Pandemic Agreement plays down primary prevention.
Lancet-PPATS Commission on Prevention of Viral Spillover; Mettenleiter TC, Winkler AS. Lancet-PPATS Commission on Prevention of Viral Spillover, et al. Lancet. 2024 Feb 10;403(10426):525-526. doi: 10.1016/S0140-6736(24)00066-7. Lancet. 2024. PMID: 38341244 No abstract available.
284 results