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CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
Guo W, Wang H, Kumar Tharkeshwar A, Couthouis J, Braems E, Masrori P, Van Schoor E, Fan Y, Ahuja K, Moisse M, Jacquemyn M, Furtado Madeiro da Costa R, Gajjar M, Balusu S, Tricot T, Fumagalli L, Hersmus N, Janky R, Impens F, Vanden Berghe P, Ho R, Thal DR, Vandenberghe R, Hegde ML, Chandran S, De Strooper B, Daelemans D, Van Damme P, Van Den Bosch L, Verfaillie C. Guo W, et al. Among authors: thal dr. Alzheimers Dement. 2023 Apr;19(4):1245-1259. doi: 10.1002/alz.12760. Epub 2022 Aug 22. Alzheimers Dement. 2023. PMID: 35993441 Free PMC article.
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study.
Van Weehaeghe D, Van Schoor E, De Vocht J, Koole M, Attili B, Celen S, Declercq L, Thal DR, Van Damme P, Bormans G, Van Laere K. Van Weehaeghe D, et al. Among authors: thal dr. J Nucl Med. 2020 Apr;61(4):604-607. doi: 10.2967/jnumed.119.231985. Epub 2019 Sep 27. J Nucl Med. 2020. PMID: 31562223 Free PMC article.
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic-pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases.
Dedeene L, Van Schoor E, Ospitalieri S, Ronisz A, Weishaupt JH, Otto M, Ludolph AC, Scheuerle A, Vandenberghe R, Van Damme P, Poesen K, Thal DR. Dedeene L, et al. Among authors: thal dr. Acta Neuropathol. 2020 Nov;140(5):777-781. doi: 10.1007/s00401-020-02216-9. Epub 2020 Aug 30. Acta Neuropathol. 2020. PMID: 32862270 No abstract available.
242 results