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Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.
Groelly FJ, Dagg RA, Petropoulos M, Rossetti GG, Prasad B, Panagopoulos A, Paulsen T, Karamichali A, Jones SE, Ochs F, Dionellis VS, Puig Lombardi E, Miossec MJ, Lockstone H, Legube G, Blackford AN, Altmeyer M, Halazonetis TD, Tarsounas M. Groelly FJ, et al. Among authors: altmeyer m. Mol Cell. 2022 Sep 15;82(18):3382-3397.e7. doi: 10.1016/j.molcel.2022.07.011. Epub 2022 Aug 23. Mol Cell. 2022. PMID: 36002001 Free PMC article.
53BP1 fosters fidelity of homology-directed DNA repair.
Ochs F, Somyajit K, Altmeyer M, Rask MB, Lukas J, Lukas C. Ochs F, et al. Among authors: altmeyer m. Nat Struct Mol Biol. 2016 Aug;23(8):714-21. doi: 10.1038/nsmb.3251. Epub 2016 Jun 27. Nat Struct Mol Biol. 2016. PMID: 27348077
The Hammer and the Dance of Cell Cycle Control.
Panagopoulos A, Altmeyer M. Panagopoulos A, et al. Among authors: altmeyer m. Trends Biochem Sci. 2021 Apr;46(4):301-314. doi: 10.1016/j.tibs.2020.11.002. Epub 2020 Dec 2. Trends Biochem Sci. 2021. PMID: 33279370 Free article. Review.
Dealing with DNA lesions: When one cell cycle is not enough.
Lezaja A, Altmeyer M. Lezaja A, et al. Among authors: altmeyer m. Curr Opin Cell Biol. 2021 Jun;70:27-36. doi: 10.1016/j.ceb.2020.11.001. Epub 2020 Dec 10. Curr Opin Cell Biol. 2021. PMID: 33310228 Free article. Review.
RPA shields inherited DNA lesions for post-mitotic DNA synthesis.
Lezaja A, Panagopoulos A, Wen Y, Carvalho E, Imhof R, Altmeyer M. Lezaja A, et al. Among authors: altmeyer m. Nat Commun. 2021 Jun 22;12(1):3827. doi: 10.1038/s41467-021-23806-5. Nat Commun. 2021. PMID: 34158486 Free PMC article.
When the RAP (80) fades out, you can hear BRCA1 RING.
Panagopoulos A, Altmeyer M. Panagopoulos A, et al. Among authors: altmeyer m. EMBO Rep. 2021 Dec 6;22(12):e54116. doi: 10.15252/embr.202154116. Epub 2021 Nov 2. EMBO Rep. 2021. PMID: 34726332 Free PMC article.
96 results