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Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells.
Mol Cell. 2022 Sep 15;82(18):3382-3397.e7. doi: 10.1016/j.molcel.2022.07.011. Epub 2022 Aug 23.
Mol Cell. 2022.
PMID: 36002001
Free PMC article.
DNA Damage and Cancer Immunotherapy: A STING in the Tale.
Reisländer T, Groelly FJ, Tarsounas M.
Reisländer T, et al. Among authors: groelly fj.
Mol Cell. 2020 Oct 1;80(1):21-28. doi: 10.1016/j.molcel.2020.07.026. Epub 2020 Aug 17.
Mol Cell. 2020.
PMID: 32810436
Free article.
Review.
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A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells.
Dagg RA, Zonderland G, Lombardi EP, Rossetti GG, Groelly FJ, Barroso S, Tacconi EMC, Wright B, Lockstone H, Aguilera A, Halazonetis TD, Tarsounas M.
Dagg RA, et al. Among authors: groelly fj.
Nat Commun. 2021 Aug 13;12(1):4919. doi: 10.1038/s41467-021-25215-0.
Nat Commun. 2021.
PMID: 34389725
Free PMC article.
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BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors.
Reisländer T, Lombardi EP, Groelly FJ, Miar A, Porru M, Di Vito S, Wright B, Lockstone H, Biroccio A, Harris A, Londoño-Vallejo A, Tarsounas M.
Reisländer T, et al. Among authors: groelly fj.
Nat Commun. 2019 Jul 17;10(1):3143. doi: 10.1038/s41467-019-11048-5.
Nat Commun. 2019.
PMID: 31316060
Free PMC article.
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Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours.
Groelly FJ, Porru M, Zimmer J, Benainous H, De Visser Y, Kosova AA, Di Vito S, Serra V, Ryan A, Leonetti C, Bruna A, Biroccio A, Tarsounas M.
Groelly FJ, et al.
EMBO Mol Med. 2022 Mar 7;14(3):e14501. doi: 10.15252/emmm.202114501. Epub 2022 Feb 2.
EMBO Mol Med. 2022.
PMID: 35107878
Free PMC article.
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High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells.
Groelly FJ, Dagg RA, Mailler J, Halazonetis TD, Tarsounas M.
Groelly FJ, et al.
STAR Protoc. 2023 Mar 17;4(1):101970. doi: 10.1016/j.xpro.2022.101970. Epub 2023 Jan 3.
STAR Protoc. 2023.
PMID: 36598851
Free PMC article.
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Targeting DNA damage response pathways in cancer.
Groelly FJ, Fawkes M, Dagg RA, Blackford AN, Tarsounas M.
Groelly FJ, et al.
Nat Rev Cancer. 2023 Feb;23(2):78-94. doi: 10.1038/s41568-022-00535-5. Epub 2022 Dec 5.
Nat Rev Cancer. 2023.
PMID: 36471053
Review.
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