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Page 1
Mycobacterium abscessus pathogenesis identified by phenogenomic analyses.
Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Wuest AW, Marshall EKP, Weimann A, Everall I, Bryant JM, Malhotra S, Bannerman BP, Kierdorf K, Blundell TL, Dionne MS, Parkhill J, Andres Floto R. Boeck L, et al. Among authors: sangen j. Nat Microbiol. 2022 Sep;7(9):1431-1441. doi: 10.1038/s41564-022-01204-x. Epub 2022 Aug 25. Nat Microbiol. 2022. PMID: 36008617 Free PMC article.
RNA Sequencing Elucidates Drug-Specific Mechanisms of Antibiotic Tolerance and Resistance in Mycobacterium abscessus.
Schildkraut JA, Coolen JPM, Burbaud S, Sangen JJN, Kwint MP, Floto RA, Op den Camp HJM, Te Brake LHM, Wertheim HFL, Neveling K, Hoefsloot W, van Ingen J. Schildkraut JA, et al. Among authors: sangen jjn. Antimicrob Agents Chemother. 2022 Jan 18;66(1):e0150921. doi: 10.1128/AAC.01509-21. Epub 2021 Oct 11. Antimicrob Agents Chemother. 2022. PMID: 34633851 Free PMC article.
Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
Thomas SE, Whitehouse AJ, Brown K, Burbaud S, Belardinelli JM, Sangen J, Lahiri R, Libardo MDJ, Gupta P, Malhotra S, Boshoff HIM, Jackson M, Abell C, Coyne AG, Blundell TL, Floto RA, Mendes V. Thomas SE, et al. Among authors: sangen j. Nucleic Acids Res. 2020 Aug 20;48(14):8099-8112. doi: 10.1093/nar/gkaa539. Nucleic Acids Res. 2020. PMID: 32602532 Free PMC article.
Minocycline Has No Clear Role in the Treatment of Mycobacterium abscessus Disease.
Ruth MM, Sangen JJN, Pennings LJ, Schildkraut JA, Hoefsloot W, Magis-Escurra C, Wertheim HFL, van Ingen J. Ruth MM, et al. Among authors: sangen jjn. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e01208-18. doi: 10.1128/AAC.01208-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30104268 Free PMC article.
Minocycline treatment for pulmonary Mycobacterium avium complex disease based on pharmacokinetics/pharmacodynamics and Bayesian framework mathematical models.
Ruth MM, Magombedze G, Gumbo T, Bendet P, Sangen JJN, Zweijpfenning S, Hoefsloot W, Pennings L, Koeken VACM, Wertheim HFL, Lee PS, van Ingen J, Deshpande D. Ruth MM, et al. Among authors: sangen jjn. J Antimicrob Chemother. 2019 Jul 1;74(7):1952-1961. doi: 10.1093/jac/dkz143. J Antimicrob Chemother. 2019. PMID: 31039251
Nifurtimox Is Ineffective against Drug-Resistant Mycobacteria.
Ruth MM, Sangen JJN, Wertheim HFL, van Ingen J. Ruth MM, et al. Among authors: sangen jjn. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e01233-17. doi: 10.1128/AAC.01233-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28652235 Free PMC article. No abstract available.