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ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance.
Ghiarone T, Castorena-Gonzalez JA, Foote CA, Ramirez-Perez FI, Ferreira-Santos L, Cabral-Amador FJ, de la Torre R, Ganga RR, Wheeler AA, Manrique-Acevedo C, Padilla J, Martinez-Lemus LA. Ghiarone T, et al. Among authors: ferreira santos l. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H688-H701. doi: 10.1152/ajpheart.00039.2022. Epub 2022 Aug 26. Am J Physiol Heart Circ Physiol. 2022. PMID: 36018759 Free PMC article.
LIMK (LIM Kinase) Inhibition Prevents Vasoconstriction- and Hypertension-Induced Arterial Stiffening and Remodeling.
Morales-Quinones M, Ramirez-Perez FI, Foote CA, Ghiarone T, Ferreira-Santos L, Bloksgaard M, Spencer N, Kimchi ET, Manrique-Acevedo C, Padilla J, Martinez-Lemus LA. Morales-Quinones M, et al. Among authors: ferreira santos l. Hypertension. 2020 Aug;76(2):393-403. doi: 10.1161/HYPERTENSIONAHA.120.15203. Epub 2020 Jun 29. Hypertension. 2020. PMID: 32594801 Free PMC article.
Cystamine reduces vascular stiffness in Western diet-fed female mice.
Ramirez-Perez FI, Cabral-Amador FJ, Whaley-Connell AT, Aroor AR, Morales-Quinones M, Woodford ML, Ghiarone T, Ferreira-Santos L, Jurrissen TJ, Manrique-Acevedo CM, Jia G, DeMarco VG, Padilla J, Martinez-Lemus LA, Lastra G. Ramirez-Perez FI, et al. Among authors: ferreira santos l. Am J Physiol Heart Circ Physiol. 2022 Feb 1;322(2):H167-H180. doi: 10.1152/ajpheart.00431.2021. Epub 2021 Dec 10. Am J Physiol Heart Circ Physiol. 2022. PMID: 34890280 Free PMC article.
Chemotherapy acutely impairs neurovascular and hemodynamic responses in women with breast cancer.
Sales ARK, Negrão MV, Testa L, Ferreira-Santos L, Groehs RVR, Carvalho B, Toschi-Dias E, Rocha NG, Laurindo FRM, Debbas V, Rondon MUPB, Mano MS, Hajjar LA, Hoff PMG, Filho RK, Negrão CE. Sales ARK, et al. Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(7):H1-H12. doi: 10.1152/ajpheart.00756.2018. Epub 2019 Apr 19. Am J Physiol Heart Circ Physiol. 2019. PMID: 31002284 Free article. Clinical Trial.
Effects of aerobic and inspiratory training on skeletal muscle microRNA-1 and downstream-associated pathways in patients with heart failure.
Antunes-Correa LM, Trevizan PF, Bacurau AVN, Ferreira-Santos L, Gomes JLP, Urias U, Oliveira PA, Alves MJNN, de Almeida DR, Brum PC, Oliveira EM, Hajjar L, Kalil Filho R, Negrão CE. Antunes-Correa LM, et al. Among authors: ferreira santos l. J Cachexia Sarcopenia Muscle. 2020 Feb;11(1):89-102. doi: 10.1002/jcsm.12495. Epub 2019 Nov 19. J Cachexia Sarcopenia Muscle. 2020. PMID: 31743617 Free PMC article.
Cerebral blood flow autoregulation in ischemic heart failure.
Caldas JR, Panerai RB, Haunton VJ, Almeida JP, Ferreira GS, Camara L, Nogueira RC, Bor-Seng-Shu E, Oliveira ML, Groehs RR, Ferreira-Santos L, Teixeira MJ, Galas FR, Robinson TG, Jatene FB, Hajjar LA. Caldas JR, et al. Am J Physiol Regul Integr Comp Physiol. 2017 Jan 1;312(1):R108-R113. doi: 10.1152/ajpregu.00361.2016. Epub 2016 Dec 7. Am J Physiol Regul Integr Comp Physiol. 2017. PMID: 27927624 Free article.
Sitting leg vasculopathy: potential adaptations beyond the endothelium.
Ferreira-Santos L, Martinez-Lemus LA, Padilla J. Ferreira-Santos L, et al. Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H760-H771. doi: 10.1152/ajpheart.00489.2023. Epub 2024 Jan 19. Am J Physiol Heart Circ Physiol. 2024. PMID: 38241008 Review.
Neuraminidase-induced externalization of phosphatidylserine activates ADAM17 and impairs insulin signaling in endothelial cells.
Ferreira-Santos L, Ramirez-Perez FI, Foote CA, Augenreich MA, McMillan NJ, Williams MB, Gonzalez-Vallejo JD, Power G, Wheeler AA, Manrique-Acevedo C, Martinez-Lemus LA, Padilla J. Ferreira-Santos L, et al. Am J Physiol Heart Circ Physiol. 2024 Jan 1;326(1):H270-H277. doi: 10.1152/ajpheart.00638.2023. Epub 2023 Nov 24. Am J Physiol Heart Circ Physiol. 2024. PMID: 37999645
16 results