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Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression.
Al-Dabet MM, Shahzad K, Elwakiel A, Sulaj A, Kopf S, Bock F, Gadi I, Zimmermann S, Rana R, Krishnan S, Gupta D, Manoharan J, Fatima S, Nazir S, Schwab C, Baber R, Scholz M, Geffers R, Mertens PR, Nawroth PP, Griffin JH, Keller M, Dockendorff C, Kohli S, Isermann B. Al-Dabet MM, et al. Among authors: isermann b. Nat Commun. 2022 Aug 27;13(1):5062. doi: 10.1038/s41467-022-32477-9. Nat Commun. 2022. PMID: 36030260 Free PMC article.
Peripheral blood mononuclear cells isolated from patients with diabetic nephropathy show increased activation of the oxidative-stress sensitive transcription factor NF-kappaB.
Hofmann MA, Schiekofer S, Isermann B, Kanitz M, Henkels M, Joswig M, Treusch A, Morcos M, Weiss T, Borcea V, Abdel Khalek AK, Amiral J, Tritschler H, Ritz E, Wahl P, Ziegler R, Bierhaus A, Nawroth PP. Hofmann MA, et al. Among authors: isermann b. Diabetologia. 1999 Feb;42(2):222-32. doi: 10.1007/s001250051142. Diabetologia. 1999. PMID: 10064103
Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study.
Morcos M, Borcea V, Isermann B, Gehrke S, Ehret T, Henkels M, Schiekofer S, Hofmann M, Amiral J, Tritschler H, Ziegler R, Wahl P, Nawroth PP. Morcos M, et al. Among authors: isermann b. Diabetes Res Clin Pract. 2001 Jun;52(3):175-83. doi: 10.1016/s0168-8227(01)00223-6. Diabetes Res Clin Pract. 2001. PMID: 11323087 Clinical Trial.
A 63bp deletion in the promoter of rage correlates with a decreased risk for nephropathy in patients with type 2 diabetes.
Rudofsky G Jr, Isermann B, Schilling T, Schiekofer S, Andrassy M, Schneider JG, Morcos M, Humpert PM, Sayed AA, Witte S, Renn W, Pfohl M, Hamann A, Nosikov V, Schleicher E, Häring HU, Rudofsky G, Ritz E, Nawroth PP, Bierhaus A. Rudofsky G Jr, et al. Among authors: isermann b. Exp Clin Endocrinol Diabetes. 2004 Mar;112(3):135-41. doi: 10.1055/s-2004-817822. Exp Clin Endocrinol Diabetes. 2004. PMID: 15052533
[AGE-RAGE: a hypothesis or a mechanism?].
Isermann B, Bierhaus A, Humpert PM, Rudofsky G, Chavakis T, Ritzel R, Wendt T, Morcos M, Kasperk C, Hamann A, Nawroth PP. Isermann B, et al. Herz. 2004 Aug;29(5):504-9. doi: 10.1007/s00059-004-2611-3. Herz. 2004. PMID: 15340736 Review. German.
The protein C system (TM EPCR).
Isermann B, Nawroth PP. Isermann B, et al. Thromb Res. 2005 Feb;115 Suppl 1:34-9. Thromb Res. 2005. PMID: 15790150 No abstract available.
241 results