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Mainstream germline genetic testing for patients with epithelial ovarian cancer leads to higher testing rates and a reduction in genetics-related healthcare costs from a healthcare payer perspective.
Bokkers K, Frederix GWJ, Velthuizen ME, van der Aa M, Gerestein CG, van Dorst EBL, Lange JG, Louwers JA, Koole W, Zweemer RP, Ausems MGEM. Bokkers K, et al. Among authors: koole w. Gynecol Oncol. 2022 Oct;167(1):115-122. doi: 10.1016/j.ygyno.2022.08.011. Epub 2022 Aug 26. Gynecol Oncol. 2022. PMID: 36031452 Free article.
FANCJ promotes DNA synthesis through G-quadruplex structures.
Castillo Bosch P, Segura-Bayona S, Koole W, van Heteren JT, Dewar JM, Tijsterman M, Knipscheer P. Castillo Bosch P, et al. Among authors: koole w. EMBO J. 2014 Nov 3;33(21):2521-33. doi: 10.15252/embj.201488663. Epub 2014 Sep 5. EMBO J. 2014. PMID: 25193968 Free PMC article.
Cancer risks for other sites in addition to breast in CHEK2 c.1100delC families.
Schreurs MAC, Schmidt MK, Hollestelle A, Schaapveld M; Hereditary Breast and Ovarian Cancer Research Group Netherlands; van Asperen CJ, Ausems MGEM, van de Beek I, Broekema MF, Collée JM, van der Hout AH, van Kaam KJAF, Komdeur FL, Mensenkamp AR, Adank MA, Hooning M. Schreurs MAC, et al. Genet Med. 2024 May 31:101171. doi: 10.1016/j.gim.2024.101171. Online ahead of print. Genet Med. 2024. PMID: 38828701
Patients' experiences with pre-test genetic counseling provided by breast cancer healthcare professionals: Results from a large prospective multicenter study.
Bokkers K, Bleiker EMA, Velthuizen ME, Koelemij R, Burgmans JPJ, Klinkenbijl JH, Schouten van der Velden AP, Vermulst N, Huizinga BF, Witkamp AJ, Frakking T, Brohet RM, Aalfs CM, Koole W, Schoenmaeckers EJP, Ausems MGEM. Bokkers K, et al. Among authors: koole w. Breast. 2023 Jun;69:349-357. doi: 10.1016/j.breast.2023.03.017. Epub 2023 Mar 29. Breast. 2023. PMID: 37018966 Free PMC article.
19 results