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Implications for sequencing of biologic therapy and choice of second anti-TNF in patients with inflammatory bowel disease: results from the IMmunogenicity to Second Anti-TNF therapy (IMSAT) therapeutic drug monitoring study.
Chanchlani N, Lin S, Auth MK, Lee CL, Robbins H, Looi S, Murugesan SV, Riley T, Preston C, Stephenson S, Cardozo W, Sonwalkar SA, Allah-Ditta M, Mansfield L, Durai D, Baker M, London I, London E, Gupta S, Di Mambro A, Murphy A, Gaynor E, Jones KDJ, Claridge A, Sebastian S, Ramachandran S, Selinger CP, Borg-Bartolo SP, Knight P, Sprakes MB, Burton J, Kane P, Lupton S, Fletcher A, Gaya DR, Colbert R, Seenan JP, MacDonald J, Lynch L, McLachlan I, Shields S, Hansen R, Gervais L, Jere M, Akhtar M, Black K, Henderson P, Russell RK, Lees CW, Derikx LAAP, Lockett M, Betteridge F, De Silva A, Hussenbux A, Beckly J, Bendall O, Hart JW, Thomas A, Hamilton B, Gordon C, Chee D, McDonald TJ, Nice R, Parkinson M, Gardner-Thorpe H, Butterworth JR, Javed A, Al-Shakhshir S, Yadagiri R, Maher S, Pollok RCG, Ng T, Appiahene P, Donovan F, Lok J, Chandy R, Jagdish R, Baig D, Mahmood Z, Marsh L, Moss A, Abdulgader A, Kitchin A, Walker GJ, George B, Lim YH, Gulliver J, Bloom S, Theaker H, Carlson S, Cummings JRF, Livingstone R, Beale A, Carter JO, Bell A, Coulter A, Snook J, Stone H, Kennedy NA, Goodhand JR, Ahmad T; IMSAT study investigators. Chanchlani N, et al. Among authors: murugesan sv. Aliment Pharmacol Ther. 2022 Oct;56(8):1250-1263. doi: 10.1111/apt.17170. Epub 2022 Aug 29. Aliment Pharmacol Ther. 2022. PMID: 36039036 Free PMC article.
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study.
Kennedy NA, Heap GA, Green HD, Hamilton B, Bewshea C, Walker GJ, Thomas A, Nice R, Perry MH, Bouri S, Chanchlani N, Heerasing NM, Hendy P, Lin S, Gaya DR, Cummings JRF, Selinger CP, Lees CW, Hart AL, Parkes M, Sebastian S, Mansfield JC, Irving PM, Lindsay J, Russell RK, McDonald TJ, McGovern D, Goodhand JR, Ahmad T; UK Inflammatory Bowel Disease Pharmacogenetics Study Group. Kennedy NA, et al. Lancet Gastroenterol Hepatol. 2019 May;4(5):341-353. doi: 10.1016/S2468-1253(19)30012-3. Epub 2019 Feb 27. Lancet Gastroenterol Hepatol. 2019. PMID: 30824404
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn's Disease.
Sazonovs A, Kennedy NA, Moutsianas L, Heap GA, Rice DL, Reppell M, Bewshea CM, Chanchlani N, Walker GJ, Perry MH, McDonald TJ, Lees CW, Cummings JRF, Parkes M, Mansfield JC, Irving PM, Barrett JC, McGovern D, Goodhand JR, Anderson CA, Ahmad T; PANTS Consortium. Sazonovs A, et al. Gastroenterology. 2020 Jan;158(1):189-199. doi: 10.1053/j.gastro.2019.09.041. Epub 2019 Oct 7. Gastroenterology. 2020. PMID: 31600487 Free article.
Enhanced neoplasia detection in chronic ulcerative colitis: the ENDCaP-C diagnostic accuracy study.
Awasthi A, Barbour J, Beggs A, Bhandari P, Blakeway D, Brookes M, Brown J, Brown M, Caldwell G, Clokie S, Colleypriest B, Conlin A, de Silva S, de Caestecker J, Deeks J, Dhar A, Dilworth M, Fogden E, Foley S, Ghosh D, Grellier L, Hart A, Hoque SS, Iacucci M, Iqbal T, James J, Jarvis M, Jayaprakash A, Keshav S, Magill L, Matthews G, Mawdsley J, McLaughlin S, Mehta S, Monahan K, Morton D, Murugesan S, Parkes M, Pestinger V, Probert C, Ramadas A, Rettino A, Sebastian S, Sharma N, Griffiths M, Stockton J, Subramanian V, Suggett N, Taniere P, Teare J, Verma AM, Wallis Y. Awasthi A, et al. Southampton (UK): NIHR Journals Library; 2021 Jan. Southampton (UK): NIHR Journals Library; 2021 Jan. PMID: 33439599 Free Books & Documents. Review.
The role of plasminogen activator inhibitor-1 in gastric mucosal protection.
Kenny S, Steele I, Lyons S, Moore AR, Murugesan SV, Tiszlavicz L, Dimaline R, Pritchard DM, Varro A, Dockray GJ. Kenny S, et al. Among authors: murugesan sv. Am J Physiol Gastrointest Liver Physiol. 2013 May 1;304(9):G814-22. doi: 10.1152/ajpgi.00017.2013. Epub 2013 Mar 14. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23494120 Free PMC article.
Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.
Kumar JD, Steele I, Moore AR, Murugesan SV, Rakonczay Z, Venglovecz V, Pritchard DM, Dimaline R, Tiszlavicz L, Varro A, Dockray GJ. Kumar JD, et al. Among authors: murugesan sv. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 15;309(2):G78-86. doi: 10.1152/ajpgi.00084.2015. Epub 2015 May 14. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25977510 Free PMC article.
Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells.
Nørsett KG, Steele I, Duval C, Sammut SJ, Murugesan SV, Kenny S, Rainbow L, Dimaline R, Dockray GJ, Pritchard DM, Varro A. Nørsett KG, et al. Among authors: murugesan sv. Am J Physiol Gastrointest Liver Physiol. 2011 Sep;301(3):G446-53. doi: 10.1152/ajpgi.00527.2010. Epub 2010 Dec 30. Am J Physiol Gastrointest Liver Physiol. 2011. PMID: 21193525 Free PMC article.
17 results