Wang S - Search Results

1

Biliary NIK promotes ductular reaction and liver injury and fibrosis in mice.

Zhang Z, Zhong X, Shen H, Sheng L, Liangpunsakul S, Lok AS, Omary MB, Wang S, Rui L. Zhang Z, et al. Among authors: wang s. Nat Commun. 2022 Aug 30;13(1):5111. doi: 10.1038/s41467-022-32575-8. Nat Commun. 2022. PMID: 36042192 Free PMC article.

2

Hepatic TRAF2 regulates glucose metabolism through enhancing glucagon responses.

Chen Z, Sheng L, Shen H, Zhao Y, Wang S, Brink R, Rui L. Chen Z, et al. Among authors: wang s. Diabetes. 2012 Mar;61(3):566-73. doi: 10.2337/db11-0474. Epub 2012 Feb 7. Diabetes. 2012. PMID: 22315325 Free PMC article.

3

Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity.

Zhou H, Lu J, Chinnaswamy K, Stuckey JA, Liu L, McEachern D, Yang CY, Bernard D, Shen H, Rui L, Sun Y, Wang S. Zhou H, et al. Among authors: wang s. Nat Commun. 2021 May 11;12(1):2621. doi: 10.1038/s41467-021-22924-4. Nat Commun. 2021. PMID: 33976147 Free PMC article.

4

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.

Asangani IA, Dommeti VL, Wang X, Malik R, Cieslik M, Yang R, Escara-Wilke J, Wilder-Romans K, Dhanireddy S, Engelke C, Iyer MK, Jing X, Wu YM, Cao X, Qin ZS, Wang S, Feng FY, Chinnaiyan AM. Asangani IA, et al. Among authors: wang x, wang s. Nature. 2014 Jun 12;510(7504):278-82. doi: 10.1038/nature13229. Epub 2014 Apr 23. Nature. 2014. PMID: 24759320 Free PMC article.

5

A potent small-molecule inhibitor of the DCN1-UBC12 interaction that selectively blocks cullin 3 neddylation.

Zhou H, Lu J, Liu L, Bernard D, Yang CY, Fernandez-Salas E, Chinnaswamy K, Layton S, Stuckey J, Yu Q, Zhou W, Pan Z, Sun Y, Wang S. Zhou H, et al. Among authors: wang s. Nat Commun. 2017 Oct 27;8(1):1150. doi: 10.1038/s41467-017-01243-7. Nat Commun. 2017. PMID: 29074978 Free PMC article.

6

Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors.

Ran X, Zhao Y, Liu L, Bai L, Yang CY, Zhou B, Meagher JL, Chinnaswamy K, Stuckey JA, Wang S. Ran X, et al. Among authors: wang s. J Med Chem. 2015 Jun 25;58(12):4927-39. doi: 10.1021/acs.jmedchem.5b00613. Epub 2015 Jun 16. J Med Chem. 2015. PMID: 26080064 Free PMC article.

7

Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression.

Zhou B, Hu J, Xu F, Chen Z, Bai L, Fernandez-Salas E, Lin M, Liu L, Yang CY, Zhao Y, McEachern D, Przybranowski S, Wen B, Sun D, Wang S. Zhou B, et al. Among authors: wang s. J Med Chem. 2018 Jan 25;61(2):462-481. doi: 10.1021/acs.jmedchem.6b01816. Epub 2017 Mar 24. J Med Chem. 2018. PMID: 28339196 Free PMC article.

8

The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity.

Zhou J, Kryczek I, Li S, Li X, Aguilar A, Wei S, Grove S, Vatan L, Yu J, Yan Y, Liao P, Lin H, Li J, Li G, Du W, Wang W, Lang X, Wang W, Wang S, Zou W. Zhou J, et al. Among authors: wang w, wang s. Nat Immunol. 2021 Apr;22(4):460-470. doi: 10.1038/s41590-021-00888-3. Epub 2021 Mar 25. Nat Immunol. 2021. PMID: 33767425 Free PMC article.

9

A small molecule compound inhibits AKT pathway in ovarian cancer cell lines.

Tang HJ, Jin X, Wang S, Yang D, Cao Y, Chen J, Gossett DR, Lin J. Tang HJ, et al. Among authors: wang s. Gynecol Oncol. 2006 Feb;100(2):308-17. doi: 10.1016/j.ygyno.2005.08.044. Epub 2005 Oct 4. Gynecol Oncol. 2006. PMID: 16209885

10

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.

Ying ZX, Jin M, Peterson LF, Bernard D, Saiya-Cork K, Yildiz M, Wang S, Kaminski MS, Chang AE, Klionsky DJ, Malek SN. Ying ZX, et al. Among authors: wang s. Clin Cancer Res. 2016 Nov 1;22(21):5383-5393. doi: 10.1158/1078-0432.CCR-16-0609. Epub 2016 Jun 7. Clin Cancer Res. 2016. PMID: 27267853 Free PMC article.

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