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Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile.
Rimbert A, Yeung MW, Dalila N, Thio CHL, Yu H, Loaiza N, Oldoni F, van der Graaf A, Wang S, Said MA, Blauw LL, Girardeau A, Bray L, Caillaud A, Bloks VW, Marrec M, Moulin P, Rensen PCN, van de Sluis B, Snieder H, Di Filippo M, van der Harst P, Tybjaerg-Hansen A, Zimmerman P, Cariou B, Kuivenhoven JA. Rimbert A, et al. Among authors: bloks vw. Arterioscler Thromb Vasc Biol. 2022 Oct;42(10):1262-1271. doi: 10.1161/ATVBAHA.122.317514. Epub 2022 Sep 1. Arterioscler Thromb Vasc Biol. 2022. PMID: 36047410 Free article.
Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases.
Zhan N, Wang B, Martens N, Liu Y, Zhao S, Voortman G, van Rooij J, Leijten F, Vanmierlo T, Kuipers F, Jonker JW, Bloks VW, Lütjohann D, Palumbo M, Zimetti F, Adorni MP, Liu H, Mulder MT. Zhan N, et al. Among authors: bloks vw. Int J Mol Sci. 2023 Jan 9;24(2):1290. doi: 10.3390/ijms24021290. Int J Mol Sci. 2023. PMID: 36674804 Free PMC article.
Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men.
Paalvast Y, Gerding A, Wang Y, Bloks VW, van Dijk TH, Havinga R, Willems van Dijk K, Rensen PCN, Bakker BM, Kuivenhoven JA, Groen AK. Paalvast Y, et al. Among authors: bloks vw. Physiol Rep. 2017 Oct;5(19):e13376. doi: 10.14814/phy2.13376. Epub 2017 Oct 16. Physiol Rep. 2017. PMID: 29038350 Free PMC article.
DNA methylation trajectories and accelerated epigenetic aging in incident type 2 diabetes.
Fraszczyk E, Thio CHL, Wackers P, Dollé MET, Bloks VW, Hodemaekers H, Picavet HS, Stynenbosch M, Verschuren WMM, Snieder H, Spijkerman AMW, Luijten M. Fraszczyk E, et al. Among authors: bloks vw. Geroscience. 2022 Dec;44(6):2671-2684. doi: 10.1007/s11357-022-00626-z. Epub 2022 Aug 10. Geroscience. 2022. PMID: 35947335 Free PMC article.
Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
van Zwol W, Rimbert A, Wolters JC, Smit M, Bloks VW, Kloosterhuis NJ, Huijkman NCA, Koster MH, Tharehalli U, de Neck SM, Bournez C, Fuh MM, Kuipers J, Rajan S, de Bruin A, Ginsberg HN, van Westen GJP, Hussain MM, Scheja L, Heeren J, Zimmerman P, van de Sluis B, Kuivenhoven JA. van Zwol W, et al. Among authors: bloks vw. Hepatology. 2023 Nov 1;78(5):1418-1432. doi: 10.1002/hep.32709. Epub 2022 Oct 12. Hepatology. 2023. PMID: 36053190 Free PMC article.
Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.
Heida A, van Dijk T, Smit M, Koehorst M, Koster M, Kloosterhuis N, Havinga R, Bloks VW, Wolters JC, de Bruin A, Kuivenhoven JA, de Boer JF, Kuipers F, van de Sluis B. Heida A, et al. Among authors: bloks vw. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Mar;1869(2):159445. doi: 10.1016/j.bbalip.2023.159445. Epub 2023 Dec 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2024. PMID: 38086439 Free article.
Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.
Hoogerland JA, Lei Y, Wolters JC, de Boer JF, Bos T, Bleeker A, Mulder NL, van Dijk TH, Kuivenhoven JA, Rajas F, Mithieux G, Haeusler RA, Verkade HJ, Bloks VW, Kuipers F, Oosterveer MH. Hoogerland JA, et al. Among authors: bloks vw. Hepatology. 2019 Dec;70(6):2171-2184. doi: 10.1002/hep.30778. Epub 2019 Jun 24. Hepatology. 2019. PMID: 31102537 Free PMC article.
103 results