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A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.
Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: charney aw. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. NPJ Genom Med. 2022. PMID: 36064543 Free PMC article.
A role for noncoding variation in schizophrenia.
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P. Roussos P, et al. Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016/j.celrep.2014.10.015. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453756 Free PMC article.
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D; CommonMind Consortium; Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK. Dobbyn A, et al. Am J Hum Genet. 2018 Jun 7;102(6):1169-1184. doi: 10.1016/j.ajhg.2018.04.011. Epub 2018 May 24. Am J Hum Genet. 2018. PMID: 29805045 Free PMC article.
Functional annotation of rare structural variation in the human brain.
Han L, Zhao X, Benton ML, Perumal T, Collins RL, Hoffman GE, Johnson JS, Sloofman L, Wang HZ, Stone MR; CommonMind Consortium; Brennand KJ, Brand H, Sieberts SK, Marenco S, Peters MA, Lipska BK, Roussos P, Capra JA, Talkowski M, Ruderfer DM. Han L, et al. Nat Commun. 2020 Jun 12;11(1):2990. doi: 10.1038/s41467-020-16736-1. Nat Commun. 2020. PMID: 32533064 Free PMC article.
Sampling the host response to SARS-CoV-2 in hospitals under siege.
Charney AW, Simons NW, Mouskas K, Lepow L, Cheng E, Le Berichel J, Chang C, Marvin R, Del Valle DM, Calorossi S, Lansky A, Walker L, Patel M, Xie H, Yi N, Yu A, Kang G, Mendoza A, Liharska LE, Moya E, Hartnett M, Hatem S, Wilkins L, Eaton M, Jamal H, Tuballes K, Chen ST, Tabachnikova A, Chung J, Harris J, Batchelor C, Lacunza J, Yishak M, Argueta K, Karekar N, Lee B, Kelly G, Geanon D, Handler D, Leech J, Stefanos H, Dawson T, Scott I, Francoeur N, Johnson JS, Vaid A, Glicksberg BS, Nadkarni GN, Schadt EE, Gelb BD, Rahman A, Sebra R, Martin G; Mount Sinai COVID-19 Biobank Team; Marron T, Beckmann N, Kim-Schulze S, Gnjatic S, Merad M. Charney AW, et al. Nat Med. 2020 Aug;26(8):1157-1158. doi: 10.1038/s41591-020-1004-3. Nat Med. 2020. PMID: 32719485 No abstract available.
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.
Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, Levey AI, Seyfried NT, Dammer EB, Duong D, Lah JJ, Haure-Mirande JV, Shackleton B, Fanutza T, Blitzer R, Kenny E, Zhu J, Haroutunian V, Katsel P, Gandy S, Tu Z, Ehrlich ME, Zhang B, Salton SR, Schadt EE. Beckmann ND, et al. Among authors: charney aw. Nat Commun. 2020 Aug 7;11(1):3942. doi: 10.1038/s41467-020-17405-z. Nat Commun. 2020. PMID: 32770063 Free PMC article.
Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege.
Charney AW, Simons NW, Mouskas K, Lepow L, Cheng E, Le Berichel J, Chang C, Marvin R, Del Valle DM, Calorossi S, Lansky A, Walker L, Patel M, Xie H, Yi N, Yu A, Kang G, Liharska LE, Moya E, Hartnett M, Hatem S, Wilkins L, Eaton M, Jamal H, Tuballes K, Chen ST, Chung J, Harris J, Batchelor C, Lacunza J, Yishak M, Argueta K, Karekar N, Lee B, Kelly G, Geanon D, Handler D, Leech J, Stefanos H, Dawson T, Scott I, Francoeur N, Johnson JS, Vaid A, Glicksberg BS, Nadkarni GN, Schadt EE, Gelb BD, Rahman A, Sebra R, Martin G; Mount Sinai COVID-19 Biobank Team; Marron T, Beckmann N, Kim-Schulze S, Gnjatic S, Merad M. Charney AW, et al. Nat Med. 2020 Sep;26(9):1493. doi: 10.1038/s41591-020-1057-3. Nat Med. 2020. PMID: 32826990 Free PMC article.
An inflammatory cytokine signature predicts COVID-19 severity and survival.
Del Valle DM, Kim-Schulze S, Huang HH, Beckmann ND, Nirenberg S, Wang B, Lavin Y, Swartz TH, Madduri D, Stock A, Marron TU, Xie H, Patel M, Tuballes K, Van Oekelen O, Rahman A, Kovatch P, Aberg JA, Schadt E, Jagannath S, Mazumdar M, Charney AW, Firpo-Betancourt A, Mendu DR, Jhang J, Reich D, Sigel K, Cordon-Cardo C, Feldmann M, Parekh S, Merad M, Gnjatic S. Del Valle DM, et al. Among authors: charney aw. Nat Med. 2020 Oct;26(10):1636-1643. doi: 10.1038/s41591-020-1051-9. Epub 2020 Aug 24. Nat Med. 2020. PMID: 32839624 Free PMC article.
124 results