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A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.
Voloudakis G, Vicari JM, Venkatesh S, Hoffman GE, Dobrindt K, Zhang W, Beckmann ND, Higgins CA, Argyriou S, Jiang S, Hoagland D, Gao L, Corvelo A, Cho K, Lee KM, Bian J, Lee JS, Iyengar SK, Luoh SW, Akbarian S, Striker R, Assimes TL, Schadt EE, Lynch JA, Merad M, tenOever BR, Charney AW; Mount Sinai COVID-19 Biobank; VA Million Veteran Program COVID-19 Science Initiative; Brennand KJ, Fullard JF, Roussos P. Voloudakis G, et al. Among authors: tenoever br. NPJ Genom Med. 2022 Sep 5;7(1):52. doi: 10.1038/s41525-022-00324-x. NPJ Genom Med. 2022. PMID: 36064543 Free PMC article.
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Blanco-Melo D, Nilsson-Payant BE, Liu WC, Uhl S, Hoagland D, Møller R, Jordan TX, Oishi K, Panis M, Sachs D, Wang TT, Schwartz RE, Lim JK, Albrecht RA, tenOever BR. Blanco-Melo D, et al. Among authors: tenoever br. Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15. Cell. 2020. PMID: 32416070 Free PMC article.
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Iskhakova M, Fernando MB, Deans PJM, Powell SK, Javidfar B, Murphy A, Peter C, Møeller R, Garcia MF, Kimura M, Iwasawa K, Crary J, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: tenoever br. bioRxiv [Preprint]. 2020 Sep 21:2020.09.20.300574. doi: 10.1101/2020.09.20.300574. bioRxiv. 2020. PMID: 32995783 Free PMC article. Updated. Preprint.
Disruption of nuclear architecture as a cause of COVID-19 induced anosmia.
Zazhytska M, Kodra A, Hoagland DA, Fullard JF, Shayya H, Omer A, Firestein S, Gong Q, Canoll PD, Goldman JE, Roussos P, tenOever BR, Overdevest JB, Lomvardas S. Zazhytska M, et al. Among authors: tenoever br. bioRxiv [Preprint]. 2021 Feb 9:2021.02.09.430314. doi: 10.1101/2021.02.09.430314. bioRxiv. 2021. PMID: 33594368 Free PMC article. Updated. Preprint.
Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.
Dobrindt K, Hoagland DA, Seah C, Kassim B, O'Shea CP, Murphy A, Iskhakova M, Fernando MB, Powell SK, Deans PJM, Javidfar B, Peter C, Møller R, Uhl SA, Garcia MF, Kimura M, Iwasawa K, Crary JF, Kotton DN, Takebe T, Huckins LM, tenOever BR, Akbarian S, Brennand KJ. Dobrindt K, et al. Among authors: tenoever br. Stem Cell Reports. 2021 Mar 9;16(3):505-518. doi: 10.1016/j.stemcr.2021.02.010. Epub 2021 Feb 13. Stem Cell Reports. 2021. PMID: 33636110 Free PMC article.
Limited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19.
Britton GJ, Chen-Liaw A, Cossarini F, Livanos AE, Spindler MP, Plitt T, Eggers J, Mogno I, Gonzalez-Reiche AS, Siu S, Tankelevich M, Grinspan LT, Dixon RE, Jha D, van de Guchte A, Khan Z, Martinez-Delgado G, Amanat F, Hoagland DA, tenOever BR, Dubinsky MC, Merad M, van Bakel H, Krammer F, Bongers G, Mehandru S, Faith JJ. Britton GJ, et al. Among authors: tenoever br. Sci Rep. 2021 Jun 25;11(1):13308. doi: 10.1038/s41598-021-92740-9. Sci Rep. 2021. PMID: 34172783 Free PMC article.
Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia.
Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF, Shayya H, McArthur NG, Moeller R, Uhl S, Omer AD, Gottesman ME, Firestein S, Gong Q, Canoll PD, Goldman JE, Roussos P, tenOever BR, Jonathan B Overdevest, Lomvardas S. Zazhytska M, et al. Among authors: tenoever br. Cell. 2022 Mar 17;185(6):1052-1064.e12. doi: 10.1016/j.cell.2022.01.024. Epub 2022 Feb 2. Cell. 2022. PMID: 35180380 Free PMC article.
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ, Dong X, Wang M, Chen Z, Ho DD, Pitt GS, Schwartz RE, tenOever BR, Evans T, Chen S. Han Y, et al. Among authors: tenoever br. Circ Res. 2022 Apr;130(7):963-977. doi: 10.1161/CIRCRESAHA.121.320518. Epub 2022 Mar 8. Circ Res. 2022. PMID: 35255712 Free PMC article.
137 results