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Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci.
Soutar MPM, Melandri D, O'Callaghan B, Annuario E, Monaghan AE, Welsh NJ, D'Sa K, Guelfi S, Zhang D, Pittman A, Trabzuni D, Verboven AHA, Pan KS, Kia DA, Bictash M, Gandhi S, Houlden H, Cookson MR, Kasri NN, Wood NW, Singleton AB, Hardy J, Whiting PJ, Blauwendraat C, Whitworth AJ, Manzoni C, Ryten M, Lewis PA, Plun-Favreau H. Soutar MPM, et al. Among authors: plun favreau h. Brain. 2022 Dec 19;145(12):4349-4367. doi: 10.1093/brain/awac325. Brain. 2022. PMID: 36074904 Free PMC article.
Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset.
Billingsley KJ, Barbosa IA, Bandrés-Ciga S, Quinn JP, Bubb VJ, Deshpande C, Botia JA, Reynolds RH, Zhang D, Simpson MA, Blauwendraat C, Gan-Or Z, Gibbs JR, Nalls MA, Singleton A; International Parkinson’s Disease Genomics Consortium (IPDGC); Ryten M, Koks S. Billingsley KJ, et al. NPJ Parkinsons Dis. 2019 May 22;5:8. doi: 10.1038/s41531-019-0080-x. eCollection 2019. NPJ Parkinsons Dis. 2019. PMID: 31123700 Free PMC article.
PINK1 in mitochondrial function.
Plun-Favreau H, Hardy J. Plun-Favreau H, et al. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11041-2. doi: 10.1073/pnas.0805908105. Epub 2008 Aug 7. Proc Natl Acad Sci U S A. 2008. PMID: 18687903 Free PMC article. No abstract available.
Culprit or Bystander: Defective Mitophagy in Alzheimer's Disease.
Xie C, Aman Y, Adriaanse BA, Cader MZ, Plun-Favreau H, Xiao J, Fang EF. Xie C, et al. Front Cell Dev Biol. 2020 Jan 17;7:391. doi: 10.3389/fcell.2019.00391. eCollection 2019. Front Cell Dev Biol. 2020. PMID: 32010698 Free PMC article. Review.
PINK1: From Parkinson's disease to mitophagy and back again.
O'Callaghan B, Hardy J, Plun-Favreau H. O'Callaghan B, et al. Among authors: plun favreau h. PLoS Biol. 2023 Jun 29;21(6):e3002196. doi: 10.1371/journal.pbio.3002196. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37384773 Free PMC article.
69 results